Ignite Creation Date:
2024-05-06 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 1:54 PM
Study NCT ID:
NCT04708080
Status:
COMPLETED
Last Update Posted:
2021-03-02
First Post:
2021-01-08
Brief Title:
Effects of Thoracic Epidural Analgesia in Geriatric Patients Undergoing Open Heart Surgery
Sponsor:
Karadeniz Technical University
Organization:
Karadeniz Technical University
Study Overview
Official Title:
Effect of Thoracic Epidural Analgesia on Short-term Outcome and Mortality in Geriatric Patients With Open Heart Surgery
Status:
COMPLETED
Status Verified Date:
2021-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Elderly patients have a higher incidence of morbidity and mortality due to the interaction of various factors such as decreased physiological reserves concomitant comorbidities multiple drug use cognitive dysfunction and frailty Surgical stress pain and associated lung complications are common problems in open heart surgeries that can affect morbidity and mortality With a good postoperative pain control and improved respiratory mechanics complications that may develop in patients can be significantly prevented and the hospital cost can be reduced and the workforce loss of patients can be reduced by reducing the length of hospital stay in the intensive care unit Thoracic epidural analgesia TEA is an anesthetic analgesia method that has positive effects on many organ systems as well as providing good pain control and is frequently used in open heart surgery The aim of this study is to investigate the effects of TEA on postoperative respiratory mechanics in geriatric patients based on analgesia levels extubation times length of stay in intensive care arterial blood gases morbidity and mortality
Detailed Description:
It has been shown that stress response suppression by providing good analgesia with local or systemic methods in the postoperative period reduces mortality and morbidity in many types of surgery Especially the physiological changes that occur with aging comorbid diseases and the drugs used in the treatment of these diseases the type of surgery performed the postoperative pain treatment and the anesthesia method chosen affect mortality and morbidity Thoracic epidural analgesia TEA has provided similar benefits in open heart surgery by suppressing stress response and increasing functional residual capacity with positive effects on the diaphragm as well as providing good analgesia with thoracic sympathetic blockTEA has positive effects on postoperative pulmonary and circulatory system in selected eligible patients It allows earlier extubation and provides excellent analgesia It has been reported that TEA combined with general anesthesia in elective cardiac surgery offers a significant advantage compared to general anesthesia in terms of intensive care and hospital stay improvement or morbidity Studies have shown that TEA reduces surgical stress response improves hemodynamic stability and reduces the incidence of myocardial ischemia after coronary artery bypass surgery CABG as well as supraventricular arrhythmias in the postoperative period
Based on these studies the investigators determined the effects of TEA combined with general anesthesia on postoperative respiratory mechanics analgesia levels extubation times length of stay in intensive care arterial blood gases effects on organ functions morbidity and mortality in geriatric patients with open heart surgery in our hospital the investigators aimed to contribute to the literature by reviewing it retrospectively
Based on these studies the investigators determined the effects of TEA combined with general anesthesia on postoperative respiratory mechanics analgesia levels extubation times length of stay in intensive care arterial blood gases effects on organ functions morbidity and mortality in geriatric patients with open heart surgery in our hospital the investigators aimed to contribute to the literature by reviewing it retrospectively
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None