Ignite Creation Date:
2024-05-06 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 1:54 PM
Study NCT ID:
NCT04709900
Status:
RECRUITING
Last Update Posted:
2022-12-12
First Post:
2021-01-12
Brief Title:
CT Stress Myocardial Perfusion Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain Syndromes
Sponsor:
Rigshospitalet Denmark
Organization:
Rigshospitalet Denmark
Study Overview
Official Title:
DYnamic CT Stress Myocardial perfusioN CT Fractional Flow Reserve and Coronary CT Angiography for Optimized treatMent Strategy In Patients With sTable Chest Pain syndromEs
Status:
RECRUITING
Status Verified Date:
2022-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DYNAMITE
Brief Summary:
The purpose of the DYNAMITE trial Dynamic CT stress myocardial perfusion CT fractional flow reserve FFR-CT and coronary CT angiography for optimized treatment strategy in patients with chest pain syndromes is to determine the ability of combined anatomical and functional cardiac CT imaging to improve morbidity and mortality in patients with suspected or known ischemic heart disease
Detailed Description:
Trial design
The DYNAMITE trial is an investigator-initiated randomised controlled open-labelled trial conducted in the Capital Region of Copenhagen Denmark
The following hypothesis will be tested
First primary hypothesis A treatment strategy guided by combined dynamic CT myocardial stress perfusion FFR-CT and CT coronary angiography improves clinical outcome compared with a conventional management strategy in patients with chronic chest pain syndromes
Second primary hypothesis A treatment strategy guided by combined dynamic CT stress myocardial perfusion FFR-CT and CT coronary angiography results in improved symptom relief compared with a conventional management strategy in patients with chronic chest pain syndromes
The DYNAMITE trial is an investigator-initiated randomised controlled open-labelled trial conducted in the Capital Region of Copenhagen Denmark
The following hypothesis will be tested
First primary hypothesis A treatment strategy guided by combined dynamic CT myocardial stress perfusion FFR-CT and CT coronary angiography improves clinical outcome compared with a conventional management strategy in patients with chronic chest pain syndromes
Second primary hypothesis A treatment strategy guided by combined dynamic CT stress myocardial perfusion FFR-CT and CT coronary angiography results in improved symptom relief compared with a conventional management strategy in patients with chronic chest pain syndromes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None