Ignite Creation Date:
2024-05-06 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 1:54 PM
Study NCT ID:
NCT04707378
Status:
UNKNOWN
Last Update Posted:
2021-01-13
First Post:
2021-01-11
Brief Title:
Navigated Repetitive Transcranial Magnetic Stimulation for Parkinsons Disease With Depression or Cognitive Impairment
Sponsor:
Guangdong Provincial Peoples Hospital
Organization:
Guangdong Provincial Peoples Hospital
Study Overview
Official Title:
Navigated Repetitive Transcranial Magnetic Stimulation for Parkinsons Disease With Depression or Cognitive Impairment
Status:
UNKNOWN
Status Verified Date:
2020-09
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Depressive symptoms are common non-motor symptoms in patients with Parkinsons disease and seriously affect the quality of life and prognosis of patients Currently treatment measures for patients with Parkinsons disease with depression are mainly limited to pharmacotherapy but the side effects of antidepressants and their interaction with anti-Parkinsonian drugs limit the use of pharmacotherapy Repetitive transcranial magnetic stimulation rTMS is a new painless and non-invasive neuromodulation technique that is commonly used in the treatment of depression As the number of people with Parkinsons disease increases in China the number of patients with Parkinsons disease and depression requiring rTMS treatment will also increase The size and shape of individual brains the distance between the stimulation coil and the responding neuronal tissue and the location and orientation of anatomical structures are all different and the use of common localization methods is usually limited by these individual anatomical differences The traditional method relies on manual positioning of the coil which is time-consuming and inefficient and it is difficult to meet the requirements of position angle and coil orientation simultaneously Studies have shown that the benefits of using navigation for rTMS treatment are up to twice as high as those of non-navigation methods Therefore precise localization is a must for the future standardized application of rTMS in the development of patients with Parkinsons disease with depression In this study we applied repetitive transcranial magnetic stimulation with neuronavigation to treat patients with Parkinsons disease and depression and reconstructed cephalometric models with individual cranial imaging data to individualize and precisely target stimulation sites making rTMS more precise and effective in treating patients with Parkinsons disease and depression and providing new avenues for further clinical and scientific research
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None