Ignite Creation Date:
2024-05-06 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 1:53 PM
Study NCT ID:
NCT04695990
Status:
UNKNOWN
Last Update Posted:
2021-01-06
First Post:
2020-11-29
Brief Title:
Study on the Clinical and Mechanism of Wenyang Huoxue Decoction in Treating Heart Failure After Myocardial Infarction
Sponsor:
Jun Li
Organization:
Guanganmen Hospital of China Academy of Chinese Medical Sciences
Study Overview
Official Title:
Study on the Clinical and Mechanism of Wenyang Huoxue Decoction in Treating Heart Failure After Myocardial Infarction
Status:
UNKNOWN
Status Verified Date:
2020-12
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a randomized double-blind placebo-controlled parallel clinical trial in a Chinese population with heart failure after myocardial infarction The objective is to observe the efficacy and safety of Wenyang huoxue fang in the treatment of heart failure after myocardial infarction
Detailed Description:
Currently there is a lack of high-quality evidence-based support for TCM treatment of heart failure after myocardial infarction In addition previous studies have found that the method of warming Yang and activating blood circulation is effective in treating coronary heart disease and the core pathogenesis of heart failure after myocardial infarction is also Yang deficiency and blood stasis Therefore this project aims to evaluate the clinical value of warming Yang and activating blood circulation in the treatment of heart failure after myocardial infarction Through pharmacological research and detection the efficacy of Wenyang huoxue prescription in heart failure rats after intervention of myocardial infarction was evaluated mir-233-ISO signaling pathway was detected before and after treatment and its mechanism of action was further clarified from the perspective of epigenetics and classical pathway of heart failure
Objective To investigate the efficacy and safety of Wenyang Huoxue fang in the treatment of heart failure after myocardial infarction
Objective To investigate the efficacy and safety of Wenyang Huoxue fang in the treatment of heart failure after myocardial infarction
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None