Ignite Creation Date:
2024-05-06 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 1:53 PM
Study NCT ID:
NCT04696172
Status:
COMPLETED
Last Update Posted:
2022-12-13
First Post:
2020-12-28
Brief Title:
Plasma Biomarkers of Cardiopulmonary Bypass Induced Acute Respiratory Distress Syndrome CPB-ARDS
Sponsor:
Huazhong University of Science and Technology
Organization:
Huazhong University of Science and Technology
Study Overview
Official Title:
Explore Potential Plasma Biomarkers of Acute Respiratory Distress Syndrome ARDS Using Proteomics Analysis in Patients Undergoing Cardiopulmonary Bypass
Status:
COMPLETED
Status Verified Date:
2022-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PBOARDS
Brief Summary:
The investigators aimed to establish a prospective cohort of patients undergoing cardiopulmonary bypass CPB in cardiac surgery from April 2021 to September 2022 in Wuhan The ARDS events ventilation time time of extubation oxygenation index for 3 days after operation were observed Plasma samples were collected before CPB and several time points after CPB Dynamic differential proteins of ARDS after CPB were screened by DIA Data independent acquisition proteomics Quantitative protein marker concentration was used to predict the occurrence of ARDS after operation the model discrimination and calibration was assessed
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None