Ignite Creation Date:
2024-05-06 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 1:53 PM
Study NCT ID:
NCT04691128
Status:
COMPLETED
Last Update Posted:
2021-10-26
First Post:
2020-12-12
Brief Title:
Desflurane and Brain Relaxation in Craniotomy
Sponsor:
Beijing Tiantan Hospital
Organization:
Beijing Tiantan Hospital
Study Overview
Official Title:
Comparison of Desflurane and Propofol for Brain Relaxation in Patients Undergoing Supratentorial Craniotomya Randomized Controlled Study
Status:
COMPLETED
Status Verified Date:
2021-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Optional brain relaxation improves the surgeons operating conditions and is likely to minimize the degree of retraction injury with the potential for providing patients with a better outcome The choice of anesthetic drugs can affect intraoperative brain relaxation Propofol suppresses brain metabolism reduces cerebral blood flow and provides satisfactory brain relaxation Desflurane is often criticized in neurosurgery due to its cerebral vasodilation and potential to increase intracranial pressure however it has been found to have a little clinical significance This study intends to compare the effects of desflurane with propofol on brain relaxation in patients with supratentorial tumors under mild hyperventilation and to provide new clinical evidence for the use of desflurane in neurosurgical anesthesia
Detailed Description:
To compare the effect of desflurane versus propofol combined with remifentanil anesthesia on brain relaxation in patients undergoing supratentorial tumor surgery with mild hyperventilation and compare the emergence time and common complications during recovery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None