Ignite Creation Date:
2024-05-06 @ 3:33 PM
Last Modification Date:
2024-10-26 @ 1:51 PM
Study NCT ID:
NCT04668963
Status:
UNKNOWN
Last Update Posted:
2021-10-07
First Post:
2020-12-08
Brief Title:
Mirror Therapy in Older Adults Post-stroke
Sponsor:
Universidad Católica San Antonio de Murcia
Organization:
Universidad Católica San Antonio de Murcia
Study Overview
Official Title:
Effectiveness of Intensively Applied Mirror Therapy on Older Adults With Post-stroke Hemiplegia a Preliminary Trial
Status:
UNKNOWN
Status Verified Date:
2021-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective The present work was carried out to determine the effectiveness of neuromuscular stimulation triggered by mirror therapy in older patients with post-stroke hemiplegia by two different intervention protocols either intensively or spaced over time
Design Prospective longitudinal study Setting Two Spanish rehabilitation centres Participants forty four aging patients 70 y with diagnosed post-stroke hemiplegia were randomly distributed to intensive intervention group 5 timesweek for 6 weeks or to spaced intervention group 3 timesweek for 10 weeks which were underwent to similar number of mirror therapy sessions n30
Main outcome measures Muscle strength and activity was measured at baseline and at the end of treatment Functional ability was also evaluated
Design Prospective longitudinal study Setting Two Spanish rehabilitation centres Participants forty four aging patients 70 y with diagnosed post-stroke hemiplegia were randomly distributed to intensive intervention group 5 timesweek for 6 weeks or to spaced intervention group 3 timesweek for 10 weeks which were underwent to similar number of mirror therapy sessions n30
Main outcome measures Muscle strength and activity was measured at baseline and at the end of treatment Functional ability was also evaluated
Detailed Description:
INTRODUCTION
Cerebral ischemia or intracranial haemorrhage are the main characteristics of cerebrovascular diseases like the stroke The disruption of the functional neuronal integrity after a stroke can affect both motor and cognitive states The most characteristic motor sequel of a stroke is hemiplegia characterized by the loss of voluntary movement muscle tone and osteotendinous reflexes from the affected hemiparetic body
Mirror therapy MT was born in the late 1990s and was initially used to treat phantom limb symptoms More recently the effectiveness of this therapy in motor rehabilitation on post-stroke hemiparetic limbs has been also described Due to its low cost and simplicity it has become one of the most widely used therapies The purpose of the MT is to perform bilateral and synchronous movements with the non-paretic limb creating an illusion of movement in the brain
The effectiveness of MT on brain injury can be explained in three ways First mirror neurons can recognize an action and activate motor learning through imitation Secondly neurological damage from a stroke usually causes inflammation and oedema that interrupts the transmission of motor information The illusion of movement created MT reawakens these motor pathways by reactivating them Finally after suffering a stroke patients have a different degree of activity in their cerebral hemispheres being much lower in the injured hemisphere The performance of MT contributes to reducing this imbalance
The MT is based on visual and somatosensory information that is processed in the central nervous system The movements of the non-paretic limb reflected in the mirror create an illusion of normal movement of the affected limb This neurophysiological phenomenon stimulates the same cortical areas that are active during movement observation somatosensory cortex premotor and primary motor cortex supplementary motor area cerebellum and basal ganglia The mirror reflection leads to additional activation of the contralateral hemisphere to the perceived limb producing an increase in the hemiparetic cortico-muscular excitability However despite its valuable role on patients with post-stroke hemiplegia its effectiveness in older subjects has not been defined so clearly
OBJECTIVE For all the above the objective of the present study was to analyse the application and effectiveness of MT in older people 70 years and to compare the benefits between an intensively applied 5 timesweek MT protocol and a more spaced over time 3 timesweek procedure
METHODOLOGY Design and participants will be explained elsewhere Main outcome measures are muscle activity after intervention
EXPECTED OUTCOMES We expect that all groups improved their muscle mobility and activity Our data will confirm what intervention is more effective
Cerebral ischemia or intracranial haemorrhage are the main characteristics of cerebrovascular diseases like the stroke The disruption of the functional neuronal integrity after a stroke can affect both motor and cognitive states The most characteristic motor sequel of a stroke is hemiplegia characterized by the loss of voluntary movement muscle tone and osteotendinous reflexes from the affected hemiparetic body
Mirror therapy MT was born in the late 1990s and was initially used to treat phantom limb symptoms More recently the effectiveness of this therapy in motor rehabilitation on post-stroke hemiparetic limbs has been also described Due to its low cost and simplicity it has become one of the most widely used therapies The purpose of the MT is to perform bilateral and synchronous movements with the non-paretic limb creating an illusion of movement in the brain
The effectiveness of MT on brain injury can be explained in three ways First mirror neurons can recognize an action and activate motor learning through imitation Secondly neurological damage from a stroke usually causes inflammation and oedema that interrupts the transmission of motor information The illusion of movement created MT reawakens these motor pathways by reactivating them Finally after suffering a stroke patients have a different degree of activity in their cerebral hemispheres being much lower in the injured hemisphere The performance of MT contributes to reducing this imbalance
The MT is based on visual and somatosensory information that is processed in the central nervous system The movements of the non-paretic limb reflected in the mirror create an illusion of normal movement of the affected limb This neurophysiological phenomenon stimulates the same cortical areas that are active during movement observation somatosensory cortex premotor and primary motor cortex supplementary motor area cerebellum and basal ganglia The mirror reflection leads to additional activation of the contralateral hemisphere to the perceived limb producing an increase in the hemiparetic cortico-muscular excitability However despite its valuable role on patients with post-stroke hemiplegia its effectiveness in older subjects has not been defined so clearly
OBJECTIVE For all the above the objective of the present study was to analyse the application and effectiveness of MT in older people 70 years and to compare the benefits between an intensively applied 5 timesweek MT protocol and a more spaced over time 3 timesweek procedure
METHODOLOGY Design and participants will be explained elsewhere Main outcome measures are muscle activity after intervention
EXPECTED OUTCOMES We expect that all groups improved their muscle mobility and activity Our data will confirm what intervention is more effective
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None