Ignite Creation Date:
2024-05-06 @ 3:32 PM
Last Modification Date:
2024-10-26 @ 1:51 PM
Study NCT ID:
NCT04666376
Status:
UNKNOWN
Last Update Posted:
2020-12-17
First Post:
2020-11-30
Brief Title:
Assessing the Technique of Ovarian Tissue Cryopreservation by Vitrification in Vietnam
Sponsor:
Mỹ Đức Hospital
Organization:
Mỹ Đức Hospital
Study Overview
Official Title:
Vitrified Ovarian Tissue in Cancer Patients Assessing the Technique in Vietnam
Status:
UNKNOWN
Status Verified Date:
2020-11
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Ovarian tissue cryopreservation OTC is a new approach on fertility preservation for young female patients with cancer It is now used by many IVF centers in the world However this is the first study which OTC by vitrification is carried on and assessed the effectiveness of the technique
Detailed Description:
Ovaries from all less than 45 year-old breast cancer patients who undergo oophorectomy by laparoscopy after treated with chemotherapy will be enrolled to the study Pieces of cortex of each patient will divide into two groups Group 1 is fresh fragments control group and group 2 is vitrified group Ovarian tissues in group 2 will be vitrified or warmed with medium and devices of Ova-kit type M Kitazato Japan
Cortex fragments of each group will have
Follicle survival evaluation by Neutral red staining
Histological evaluation by Hematoxylin and Eosin staining
Evaluation relative Growth Differentiation Factor 9 GDF-9 and Caspase-3 gene expression by real-time Polymerase chain reaction PCR
Comparison of data collected from 2 groups will be carried on to evaluate the effectiveness of the technique before applying this technique for cancer patients in Vietnam
Cortex fragments of each group will have
Follicle survival evaluation by Neutral red staining
Histological evaluation by Hematoxylin and Eosin staining
Evaluation relative Growth Differentiation Factor 9 GDF-9 and Caspase-3 gene expression by real-time Polymerase chain reaction PCR
Comparison of data collected from 2 groups will be carried on to evaluate the effectiveness of the technique before applying this technique for cancer patients in Vietnam
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None