Ignite Creation Date:
2024-05-06 @ 3:32 PM
Last Modification Date:
2024-10-26 @ 1:51 PM
Study NCT ID:
NCT04668898
Status:
RECRUITING
Last Update Posted:
2024-03-20
First Post:
2020-12-09
Brief Title:
LRRK2 GBA and Other Genetic Biomarkers in Eastern European Ashkenazi Jews With and Without Parkinsons Disease
Sponsor:
Icahn School of Medicine at Mount Sinai
Organization:
Icahn School of Medicine at Mount Sinai
Study Overview
Official Title:
Dissecting Oligogenic Biomarkers in Ashkenazi Jews With Parkinsons Disease
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BioPD
Brief Summary:
Single site observational study focused on elucidating the genes and biochemical pathways involved in causing Parkinson disease
Detailed Description:
This single site study is enrolling Parkinson disease PD patients and their family members and is limited to participants of Ashkenazi Eastern European Jewish descent with GBA and LRRK2 mutations or with 3 or more family members with PD Follow-up will be for three years Participants must be in the New York City area yearly and willing to come to Mount Sinai Downtown for yearly 2 hour study visits which include obtaining personal medical and family history information blood urine and spinal fluid samples neurological exam and neuropsychiatric testing De-identified data and samples will be securely stored at a central NIH-run repository for access by other researchers Spinal fluid collection is encouraged but optional
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1U01NS107016-01A1 | NIH | None | httpsreporternihgovquickSearch1U01NS107016-01A1 |