Ignite Creation Date:
2024-05-06 @ 3:31 PM
Last Modification Date:
2024-10-26 @ 1:51 PM
Study NCT ID:
NCT04665349
Status:
COMPLETED
Last Update Posted:
2020-12-11
First Post:
2020-12-06
Brief Title:
Effect of Fasting on the Non-invasive Measurement of the Bodys Water Compartments
Sponsor:
Medical University of Gdansk
Organization:
Medical University of Gdansk
Study Overview
Official Title:
Effect of Fasting on the Non-invasive Measurement of the Bodys Water Compartments
Status:
COMPLETED
Status Verified Date:
2020-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Preoperative fasting is defined as refraining from food for at least 6 hours and clear fluids for at least 2 hours prior to anaesthesia On the one hand it is a procedure that reduces the risk of aspiration of food content and the occurrence of Mendelsons syndrome and on the other hand it was considered to be the cause of disturbances in water management in patients undergoing general anaesthesia However reports from recent years have found that moderate preoperative fasting does not influence the risk of hypovolemia in anesthetized patients It is also known that in fasting people the total body water is reduced Thus it can be assumed that there are mechanisms causing the movement of extravascular water into the lumen of blood vessels For several years the Body Composition Monitor BCM device for non-invasive measurement of the volume of individual water compartments of the human body has been available on the market It allows to determine the volume of total body water intracellular body water and extracellular body water It is mainly used during dialysis but it can also be used in other circumstances that require the determination of the bodys hydration status The principle of this method is based on non-invasive bioimpedance measurement with the use of 4 electrodes placed on two extremities
The aim of the study is to determine whether there is a fluid shift between the intracellular and extracellular compartments in people undergoing preoperative fasting Examination of this issue would allow for the development of hypothesis regarding the optimal perioperative fluid therapy If there was a shift of fluid from the intracellular space it seems more rational to supplement fluid deficiencies resulting from starvation with a 5 glucose solution If on the other hand no fluid shift from the intracellular space was detected which would suggest shifts within the extracellular space it would be advisable to hydrate the patient with crystalloid solutions
The aim of the study is to determine whether there is a fluid shift between the intracellular and extracellular compartments in people undergoing preoperative fasting Examination of this issue would allow for the development of hypothesis regarding the optimal perioperative fluid therapy If there was a shift of fluid from the intracellular space it seems more rational to supplement fluid deficiencies resulting from starvation with a 5 glucose solution If on the other hand no fluid shift from the intracellular space was detected which would suggest shifts within the extracellular space it would be advisable to hydrate the patient with crystalloid solutions
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None