Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005495
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-05-25
Brief Title:
Primary Prevention of CHD Risk Factors Occurring in US
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2002-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the effectiveness of primary prevention of coronary heart disease risk factors by examining data from the National Health Examination Survey NHES and the National Health and Nutrition Examination Surveys NHANES to determine whether more recent birth cohorts were attaining lower blood pressure and cholesterol levels than earlier birth cohorts
Detailed Description:
BACKGROUND
The coronary heart disease risk factor profile of Americans has been improving with decreasing blood pressure and cholesterol levels However it is not apparent whether this improvement is due to primary prevention of risk factors through lifestyle choices or to secondary prevention management of established risk factors Since secondary prevention only targets people with high blood pressure or cholesterol levels the effect should be demonstrated by temporal declines in the upper percentiles 75th 90th of the blood pressure and cholesterol distributions Primary prevention should shift the entire risk factor distribution including the percentiles in the middle 50th and lower 10th 25th portions of the distribution Thus the effectiveness of primary prevention programs can be evaluated by examining temporal changes in the middle and lower percentiles and the effectiveness of secondary prevention can be evaluated by examining temporal changes in the higher percentiles
DESIGN NARRATIVE
Data from the National Health Examination Survey and the National Health and Nutrition Examination Surveys were examined to determine whether more recent birth cohorts were attaining lower blood pressure and cholesterol levels than earlier birth cohorts The results of these analyses provided information that may help guide further research and application of population prevention strategies
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
The coronary heart disease risk factor profile of Americans has been improving with decreasing blood pressure and cholesterol levels However it is not apparent whether this improvement is due to primary prevention of risk factors through lifestyle choices or to secondary prevention management of established risk factors Since secondary prevention only targets people with high blood pressure or cholesterol levels the effect should be demonstrated by temporal declines in the upper percentiles 75th 90th of the blood pressure and cholesterol distributions Primary prevention should shift the entire risk factor distribution including the percentiles in the middle 50th and lower 10th 25th portions of the distribution Thus the effectiveness of primary prevention programs can be evaluated by examining temporal changes in the middle and lower percentiles and the effectiveness of secondary prevention can be evaluated by examining temporal changes in the higher percentiles
DESIGN NARRATIVE
Data from the National Health Examination Survey and the National Health and Nutrition Examination Surveys were examined to determine whether more recent birth cohorts were attaining lower blood pressure and cholesterol levels than earlier birth cohorts The results of these analyses provided information that may help guide further research and application of population prevention strategies
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R03HL058697 | NIH | None | httpsreporternihgovquickSearchR03HL058697 |