Ignite Creation Date:
2024-05-05 @ 1:18 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001201
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Evaluation of Neuromuscular Disease
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Evaluation of Neuromuscular Diseases
Status:
COMPLETED
Status Verified Date:
2002-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The peripheral nervous system is the portion of the nervous system outside of the brain and spinal cord It includes the 12 pairs of cranial nerves 31 pairs of spinal nerves and their branches nerves responsible for sensation and maintenance of normal body functions sympathetic and parasympathetic nerves
Years of research using clinical examinations microscopic examinations and electrophysiology have made the peripheral nervous system the best-studied and most available portion of the nervous system However even with all of the extensive studies conducted on the peripheral nervous system many conditions remain unclassified
The EMG Laboratory at the NIH concentrates on studying disorders of the peripheral nervous system This protocol was designed to allow the EMG Laboratory to
I Learn more about established diseases of the peripheral nervous system
II Identify and characterize new diseases of the peripheral nervous system
III Assess current techniques in the diagnosis of diseases of the peripheral nervous system
IV Refine old methods and develop new ones for the diagnosis of diseases of the peripheral nervous system
Years of research using clinical examinations microscopic examinations and electrophysiology have made the peripheral nervous system the best-studied and most available portion of the nervous system However even with all of the extensive studies conducted on the peripheral nervous system many conditions remain unclassified
The EMG Laboratory at the NIH concentrates on studying disorders of the peripheral nervous system This protocol was designed to allow the EMG Laboratory to
I Learn more about established diseases of the peripheral nervous system
II Identify and characterize new diseases of the peripheral nervous system
III Assess current techniques in the diagnosis of diseases of the peripheral nervous system
IV Refine old methods and develop new ones for the diagnosis of diseases of the peripheral nervous system
Detailed Description:
Combined with careful clinical examination electrophysiology and histopathology have rendered the peripheral nervous system the best studied and most accessible level of the nervous system But even after intensive diagnostic evaluation of peripheral neuropathies in large diagnostic centers 24 to 70 of disorders remain unclassified Analogous statistics for disorders of muscle and neuromuscular transmission are not known but probably similar if not worse Clearly detailed diagnostic characterization of disorders of the peripheral nervous system is the first stage in clinical intervention
Currently the EMG Laboratory at the NIH offers complete clinical electrophysiologic and when appropriate pathologic evaluations on all referrals from the other Branches and Institutes Since these referrals come primarily from within the NIH most disorders are secondary to other systemic disease This protocol is designed to extend the services to direct referrals of primary disorders of the peripheral nervous system The purposes are first to learn more about established diseases second to identify and characterize new diseases third to assess current methodologies and technologies and fourth to refine old methods and develop new ones Under this umbrella protocol individual cases and clinical series can be investigated
Currently the EMG Laboratory at the NIH offers complete clinical electrophysiologic and when appropriate pathologic evaluations on all referrals from the other Branches and Institutes Since these referrals come primarily from within the NIH most disorders are secondary to other systemic disease This protocol is designed to extend the services to direct referrals of primary disorders of the peripheral nervous system The purposes are first to learn more about established diseases second to identify and characterize new diseases third to assess current methodologies and technologies and fourth to refine old methods and develop new ones Under this umbrella protocol individual cases and clinical series can be investigated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 84-N-0203 | None | None | None |