Ignite Creation Date:
2024-05-06 @ 3:31 PM
Last Modification Date:
2024-10-26 @ 1:50 PM
Study NCT ID:
NCT04651101
Status:
COMPLETED
Last Update Posted:
2020-12-07
First Post:
2020-11-25
Brief Title:
Vitamin D Deficiency in Coronary Artery Disease
Sponsor:
Shiraz University of Medical Sciences
Organization:
Shiraz University of Medical Sciences
Study Overview
Official Title:
Can Vitamin D Deficiency be a Risk Factor of Coronary Artery Disease
Status:
COMPLETED
Status Verified Date:
2020-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Large population cross sectional study was conducted between 2018-2020 by attendance of 4526 patients in shiraz Iran Patients were undergone selective coronary angiography from radial artery approach by an expert interventional cardiologist 25-hydroxy vitamin D and Hs-CRP levels were measured for all patients
Detailed Description:
This cross-sectional study was conducted in Shiraz Clinical data were collected from the patients of Professor Kojuri cardiovascular clinic in Shiraz Iran Iran Fars Province Shiraz Niayesh Boulevard Email kojurijyahoocom webpage httpkojuricliniccom who came to clinic from March 2018 to March 2020 Inclusion criteria was all of the new patients who referred to Professor Kojuri cardiovascular clinic Exclusion criteria were patients with more than 100ngml 25-hydroxy vitamin D3 serum level parathyroid disorders end-stage-renal-disease ESRD and paraneoplastic syndromes Patients with more than 10mgL Hs-CRP serum level also were excluded
Complete history and physical exam were taken from the patients and risk factors such as hypertension diabetes mellitus age and gender were considered 25-hydroxy vitamin D3 was checked for all patients Blood pressure and took electrocardiography ECG for all patients were done The dependent variable was the prevalence of Coronary Artery disease the independent variable was vitamin D deficiency and intervening factors were age gender hypertension diabetes mellitus and level of Hs-CRP
All Patients were undergone selective coronary angiography from radial artery approach by an expert interventional cardiologist Angiography videos were reviewed by a team of expert cardiologists Based on the results of coronary angiography patients were classified as non-significant CAD with stenosis less than 50 and significant CAD with stenosis more than 50 stenosis In this review diabetic and hypertensive patients is considered by criteria of American diabetes association 2018 American heart association 2017 Patients serum level of 25-hydroxy vitamin D on their first visit was considered as index of vitamin D level Vitamin D deficiency and sufficiency are defined respectively as serum level of 25-hydroxy vitamin D less than 30ngml and serum level of 25-hydroxy vitamin D more than 30 ngml Patients with Parathyroid disorders and paraneoplastic syndromes were excluded
Complete history and physical exam were taken from the patients and risk factors such as hypertension diabetes mellitus age and gender were considered 25-hydroxy vitamin D3 was checked for all patients Blood pressure and took electrocardiography ECG for all patients were done The dependent variable was the prevalence of Coronary Artery disease the independent variable was vitamin D deficiency and intervening factors were age gender hypertension diabetes mellitus and level of Hs-CRP
All Patients were undergone selective coronary angiography from radial artery approach by an expert interventional cardiologist Angiography videos were reviewed by a team of expert cardiologists Based on the results of coronary angiography patients were classified as non-significant CAD with stenosis less than 50 and significant CAD with stenosis more than 50 stenosis In this review diabetic and hypertensive patients is considered by criteria of American diabetes association 2018 American heart association 2017 Patients serum level of 25-hydroxy vitamin D on their first visit was considered as index of vitamin D level Vitamin D deficiency and sufficiency are defined respectively as serum level of 25-hydroxy vitamin D less than 30ngml and serum level of 25-hydroxy vitamin D more than 30 ngml Patients with Parathyroid disorders and paraneoplastic syndromes were excluded
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None