Viewing Study NCT04635293



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Last Modification Date: 2024-10-26 @ 1:49 PM
Study NCT ID: NCT04635293
Status: COMPLETED
Last Update Posted: 2020-11-19
First Post: 2020-11-09

Brief Title: Preoperative Infusion of Levosimendan in Patients Undergoing Cardiac Surgery
Sponsor: Aretaieion University Hospital
Organization: Aretaieion University Hospital

Study Overview

Official Title: Preoperative Infusion of Levosimendan in High Risk Cardiac Surgery Patients A Retrospective Study
Status: COMPLETED
Status Verified Date: 2020-11
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The aim of this retrospective study will be to investigate the effect of the preoperative administration of levosimendan on the outcome of patients with compromised cardiac function undergoing cardiac surgery
Detailed Description: Patients with severely reduced left ventricular ejection fraction LVEF face a high risk of morbidity and mortality after cardiac surgery Impaired cardiac function preoperatively predisposes patients to low cardiac output syndrome Levosimendan acts by a different mechanism than traditional inotropes and its preoperative use could improve the outcome of patients with cardiac failure Specifically it promotes vasodilation of coronary pulmonary and systemic vessels has an anti-inflammatory and anti-oxidant effect and enhances cardiac contractility by improving the response of the myofilaments to intracellular calcium

The aim of this retrospective study will be to investigate the effect of the preoperative administration of levosimendan on the outcome of patients with compromised cardiac function undergoing cardiac surgery

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None