Ignite Creation Date:
2024-05-06 @ 3:22 PM
Last Modification Date:
2024-10-26 @ 1:48 PM
Study NCT ID:
NCT04614883
Status:
COMPLETED
Last Update Posted:
2021-06-16
First Post:
2020-11-02
Brief Title:
Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in the Context of Suspicion of COVID-19 Infection
Sponsor:
Hopital Foch
Organization:
Hopital Foch
Study Overview
Official Title:
Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in Patients Referred to the Emergency Reception Service for Suspected COVID-19 Infection Diagnostic Value and for Rapid Screening
Status:
COMPLETED
Status Verified Date:
2021-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
VOC-COVID-Diag
Brief Summary:
In the context of the actual pandemia of the Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 which requires a better diagnostic strategy for the management of patients
The study of volatile organic compounds VOC detected in exhaled air or in sweat is an innovative research area for respiratory diseases The analysis of VOC can be done either by the technique of the mass spectrometry which allows the identification of each VOC in the exhaled air or by the technique of electronic nose simpler and faster which provides an idea of the general profile of the VOC without identifying them The VOC have shown their interest in some situations such as diagnostic or prognostic tool in patients followed for thoracic tumorous pathology or bronchial or pulmonary vascular diseases
Moreover it has recently been shown that properly trained dogs would be able to detect an olfactory signature of SARS-CoV-2 infection with a specificity greater than 90 this olfactory signature corresponds to VOCs detectable by the flair of dogs Nosaïs-Covid19 study
Validation of the diagnostic value of VOC analyzes by non-invasive and rapid methods electronic nose analysis or mass spectrometry detection by the scent of dogs for the rapid detection and early diagnosis of a SARS-CoV-2 infection warrants the performance of this clinical study
The study of volatile organic compounds VOC detected in exhaled air or in sweat is an innovative research area for respiratory diseases The analysis of VOC can be done either by the technique of the mass spectrometry which allows the identification of each VOC in the exhaled air or by the technique of electronic nose simpler and faster which provides an idea of the general profile of the VOC without identifying them The VOC have shown their interest in some situations such as diagnostic or prognostic tool in patients followed for thoracic tumorous pathology or bronchial or pulmonary vascular diseases
Moreover it has recently been shown that properly trained dogs would be able to detect an olfactory signature of SARS-CoV-2 infection with a specificity greater than 90 this olfactory signature corresponds to VOCs detectable by the flair of dogs Nosaïs-Covid19 study
Validation of the diagnostic value of VOC analyzes by non-invasive and rapid methods electronic nose analysis or mass spectrometry detection by the scent of dogs for the rapid detection and early diagnosis of a SARS-CoV-2 infection warrants the performance of this clinical study
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None