Ignite Creation Date:
2024-05-06 @ 3:21 PM
Last Modification Date:
2024-10-26 @ 1:48 PM
Study NCT ID:
NCT04608240
Status:
UNKNOWN
Last Update Posted:
2021-12-02
First Post:
2020-10-02
Brief Title:
Surgical Pleth Index Predicting the Optimal Timing for Tracheal Intubation During General Anesthesia
Sponsor:
Fudan University
Organization:
Fudan University
Study Overview
Official Title:
Dose Surgical Pleth Index Play a Role to Predict Optimal Timing for Tracheal Intubation During Anesthetic Induction
Status:
UNKNOWN
Status Verified Date:
2021-11
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Surgical pleth index SPI has been widely investigated in assessing the nociceptive level and tracheal intubation is a noxious stimulus during the induction of anesthesia This study aims to evaluate the ability of SPI to predict hemodynamic reactivity after tracheal intubation and find the target value of SPI to guide the optimal timing for tracheal intubation
Detailed Description:
The surgical pleth index SPImonitored by a oxygen saturation Spo2 probe is a dimensionless score which is based on the photoplethysmographic analysis of the pulse wave and the heartbeat interval SPI score monitored during surgery is the indicator that may reflect a patients autonomic response to certain noxious stimulus and is correlated to hisher nociception level Once noxious stimulus occur sympathetically-mediated vasoconstriction and cardiac autonomic tone increasing can be reflected by SPI Several studies have since investigated the potential benefits of SPI-guided anesthesia such as SPI could reduce the intraoperative opioid consumption and facilitate extubation after surgeryJain N et al found that the need for postoperative analgesics decreased although fentanyl consumption increased when SPI guided opioid use Intraoperatively The level of SPI was also reported to be able to predict postoperative pain which could guide clinical use of opioids and improve patient postoperative satisfaction
Recent studies on SPI mainly focus on the maintenance period of anesthesia and postoperative analgesia and there is few studies on the application of SPI in anesthesia induction period Hemodynamic stability in induction period has always been the technical key point that anesthesiologists pay attention to especially for patients with cardiovascular and cerebrovascular diseases maintaining hemodynamic stability is particularly important Endotracheal intubation is a common procedure during general anesthesia The hemodynamic fluctuation caused by intubation stimulation is usually caused by the premature timing of intubation
At present the timing of intubation is much depended on the clinical experience of an anesthesiologist such as according to the degree of blood pressure heart rate decline or predicted onset of propofolopioid and neuromascular blocker This study aims to explore whether the SPI can be used in quantitative prediction of intubation timing or prediction the hemodynamic reactivity after intubation and to investigate the influence of age and gender on SPI value
Recent studies on SPI mainly focus on the maintenance period of anesthesia and postoperative analgesia and there is few studies on the application of SPI in anesthesia induction period Hemodynamic stability in induction period has always been the technical key point that anesthesiologists pay attention to especially for patients with cardiovascular and cerebrovascular diseases maintaining hemodynamic stability is particularly important Endotracheal intubation is a common procedure during general anesthesia The hemodynamic fluctuation caused by intubation stimulation is usually caused by the premature timing of intubation
At present the timing of intubation is much depended on the clinical experience of an anesthesiologist such as according to the degree of blood pressure heart rate decline or predicted onset of propofolopioid and neuromascular blocker This study aims to explore whether the SPI can be used in quantitative prediction of intubation timing or prediction the hemodynamic reactivity after intubation and to investigate the influence of age and gender on SPI value
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None