Ignite Creation Date:
2024-05-06 @ 3:21 PM
Last Modification Date:
2024-10-26 @ 1:48 PM
Study NCT ID:
NCT04607993
Status:
COMPLETED
Last Update Posted:
2022-12-05
First Post:
2020-10-28
Brief Title:
Study on the Effectiveness and Feasibility of Prone Position Ventilation Technology in Congenital Heart Disease
Sponsor:
Childrens Hospital of Fudan University
Organization:
Childrens Hospital of Fudan University
Study Overview
Official Title:
Study on the Effectiveness and Feasibility of Prone Position Ventilation Technique for Postoperative Acute Lung Injury in Infants With Congenital Heart Disease
Status:
COMPLETED
Status Verified Date:
2022-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was to compare the effects of conventional lying position and prone position ventilation on infants with acute lung injury after surgery for congenital heart disease To explore the effectiveness and feasibility of prone position ventilation for children with acute lung injury after congenital heart disease surgery
Detailed Description:
The prone position has been used to treat severe hypoxemia in patients with acute respiration dysfunction syndrome ARDS since the 1970s and it has significant effectiveness in improving gas exchange Acute lung injury ALI is a common complication after congenital heart disease The clinical manifestation is refractory hypoxemia At present mechanical ventilation is one of the main methods for the treatment of acute lung injury-induced respiratory distress syndrome Prone position ventilation refers to placing the patient in the prone position during mechanical ventilation to expand the lungs in the atelectasis area and improve the ratio of lung ventilation and perfusion
Prone position ventilation technology as an important lung protection ventilation strategy has been widely used clinically at home and abroad Compared with adults children are more convenient and easy to implement Due to the exact mechanism of improving oxygenation function the current domestic and foreign development of pediatric prone ventilation technology is mainly focused on children with ARDS There are few studies on high-quality application effects after pediatric cardiac surgery and almost no research has been carried out especially for pediatric heart The indications for the implementation of the prone position after the disease surgery the specific standardized process including the position angle the prone duration plan etc all need to be studied Therefore there is an urgent need to develop prone position ventilation technology for critically ill children with congenital heart disease after surgery to reduce postoperative pulmonary complications and shorten the time of mechanical ventilation
Prone position ventilation technology as an important lung protection ventilation strategy has been widely used clinically at home and abroad Compared with adults children are more convenient and easy to implement Due to the exact mechanism of improving oxygenation function the current domestic and foreign development of pediatric prone ventilation technology is mainly focused on children with ARDS There are few studies on high-quality application effects after pediatric cardiac surgery and almost no research has been carried out especially for pediatric heart The indications for the implementation of the prone position after the disease surgery the specific standardized process including the position angle the prone duration plan etc all need to be studied Therefore there is an urgent need to develop prone position ventilation technology for critically ill children with congenital heart disease after surgery to reduce postoperative pulmonary complications and shorten the time of mechanical ventilation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None