Ignite Creation Date:
2024-05-06 @ 3:21 PM
Last Modification Date:
2024-10-26 @ 1:47 PM
Study NCT ID:
NCT04602767
Status:
RECRUITING
Last Update Posted:
2024-03-29
First Post:
2020-10-20
Brief Title:
Low Dose Vasopressin vs Phenylephrine in Cardiac Surgery
Sponsor:
Thomas Jefferson University
Organization:
Thomas Jefferson University
Study Overview
Official Title:
Low Dose Vasopressin vs Phenylephrine in Cardiac Surgery
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a randomized open label study to investigate vasopressin versus phenylephrine as a first line pressor in cardiac surgery All patients 18 years of age presenting for coronary artery bypass graft CABG valve surgery or combined CABG and valve surgery will be screened for inclusion Patients with ejection fraction 35 moderate pulmonary hypertension mild right ventricular dysfunction a planned radial arterial graft or circulatory arrest will be excluded Patients will be randomized to receive either vasopressin or phenylephrine as the first line vasopressor during the perioperative period to maintain mean arterial blood pressure 65 mmhg Primary outcome is acute kidney injury Secondary outcomes are 30-day mortality stroke myocardial infarction re-operation sternal infection atrial fibrillation intensive care unit length of stay and total vasopressor hours
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None