Ignite Creation Date:
2024-05-06 @ 3:21 PM
Last Modification Date:
2024-10-26 @ 1:48 PM
Study NCT ID:
NCT04607525
Status:
COMPLETED
Last Update Posted:
2021-03-01
First Post:
2020-10-19
Brief Title:
Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy
Sponsor:
Ain Shams University
Organization:
Ain Shams University
Study Overview
Official Title:
Efficacy of Dexmedetomidine Infusion Without Loading Dose on Hemodynamic Variables and Recovery Time During Craniotomy A Randomized Double Blinded Controlled Study
Status:
COMPLETED
Status Verified Date:
2021-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There is no clear consensus among neuroanesthesiologists regarding which anesthetic regimen is optimal for craniotomy Propofol and short-acting opioids such as remifentanil fentanyl or sufentanil are commonly used However use of opioids is associated with increased risk of respiratory depression and postoperative nausea and vomiting Dexmedetomidine is a highly selective α2-adrenoreceptor agonist that has been considered as a useful and safe adjunct to anesthesia for various surgical procedures
Detailed Description:
The investigators designed this randomized double-blind study to evaluate the effectiveness of administration of Dexmedetomidine infusion at a dose of 05 µgkgh without loading dose during elective supratentorial craniotomy under GA The investigators will compare intraoperative hemodynamics in both groups intraoperative analgesic consumption intraoperative blood loss postoperative sedation scores intraoperative need for rescue hypotensive agents and finally the satisfaction of surgeons
To our knowledge the present study is the first to evaluate the effect of Dexmedetomidine infusion without loading dose in elective supratentorial craniotomy
To our knowledge the present study is the first to evaluate the effect of Dexmedetomidine infusion without loading dose in elective supratentorial craniotomy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None