Ignite Creation Date:
2024-05-06 @ 3:18 PM
Last Modification Date:
2024-10-26 @ 1:47 PM
Study NCT ID:
NCT04589702
Status:
COMPLETED
Last Update Posted:
2020-10-19
First Post:
2020-10-05
Brief Title:
Temporal Activation of Core Muscles and Vasti in Isolated Patellofemoral Osteoarthritis
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Temporal Activation of Core Muscles and Vasti in Isolated Patellofemoral Osteoarthritis During Stair-stepping
Status:
COMPLETED
Status Verified Date:
2020-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective To compare the temporal muscle activation between females with PF OA and normal controls during stair ascent Methods An observational comparative study was conducted with thirty-one females with PF OA and 11 healthy ones The onset times of multifidus transversus abdominus TrA gluteus medius GM and vasti muscles were measured by quantitative Electromyography during stair ascent task hypothesis Investigators hypothesized that there wont be a significant difference between females with PF OA and their matched healthy group regarding the onset times of vastus medialis obliqus VMO vastus lateralis VL gluteus medius GM multifidus and transversus abdominus TrA during stair ascent task
Detailed Description:
Investigators collected the EMG activity of VMO VL GM multifidus and TrA using bipolar Ag-AgCl disposable surface electrodes Better signal solution medical supply Co limited Zhongshan China and eight channels high-resolution wireless bio amplifier WBA system Biomation Almonte Canada Electromyographic data were sampled at 1000 Hz and bandpass filtered at 50-200 Hz
For each muscle three electrodes were used two electrodes were placed 30 mm apart in the direction of the muscle fibers and a ground electrode was placed over the closest bony prominence Before placement of the electrodes the subjects skin was cleaned with alcohol to reduce impedance and excess hair was removed to eliminate shifting of the electrodes if needed
The stair-stepping task consisted of ascending 2 steps each step was 40 cm in width 20 cm in height without handrails The depth of the first and second steps was 30 cm and 40 cm respectively Participants were asked to stand on the floor confronting the stairs and 20 cm away from the edge of the initial step The stair ascent task was performed barefooted while arms hanged at the side of the body Patients started ascending the steps immediately in response to a command at their normal speed with their affected limb Investigators didnt control the speed of stair ascent because controlling the timing of stair-stepping can alter the electromyographic signal as shown earlier for gait in asymptomatic subjects Healthy subjects started ascending stairs with their dominant limb
Before data acquisition participants performed one practice trial of stair ascent to get familiarized with the task Then the participants performed three test trials with thirty seconds of rest after each trial to prevent fatigue The raw data were stored on a personal computer for analysis with a custom program in Matlab Math Works Natick Massachusetts USA Investigators used a mean of data in three trials for analysis
Statistical Analysis
Data management and analysis were conducted using the statistical package for social studies SPSS version 22 for windows IBM SPSS Chicago IL USA Normal distribution of the data was tested using the Shapiro-Wilk test The homogeneity of variances between groups was examined using Levenes test Descriptive data are expressed as mean standard deviation An independent t-test was conducted for comparison of subject characteristics age body mass index BMI weight and height between both groups A univariate test of one way MANOVA was performed to compare EMG onset of each muscle between both groups Post-hoc analysis using the Bonferroni method was carried out for subsequent multiple comparison The level of significance for all statistical tests was set at p 005
For each muscle three electrodes were used two electrodes were placed 30 mm apart in the direction of the muscle fibers and a ground electrode was placed over the closest bony prominence Before placement of the electrodes the subjects skin was cleaned with alcohol to reduce impedance and excess hair was removed to eliminate shifting of the electrodes if needed
The stair-stepping task consisted of ascending 2 steps each step was 40 cm in width 20 cm in height without handrails The depth of the first and second steps was 30 cm and 40 cm respectively Participants were asked to stand on the floor confronting the stairs and 20 cm away from the edge of the initial step The stair ascent task was performed barefooted while arms hanged at the side of the body Patients started ascending the steps immediately in response to a command at their normal speed with their affected limb Investigators didnt control the speed of stair ascent because controlling the timing of stair-stepping can alter the electromyographic signal as shown earlier for gait in asymptomatic subjects Healthy subjects started ascending stairs with their dominant limb
Before data acquisition participants performed one practice trial of stair ascent to get familiarized with the task Then the participants performed three test trials with thirty seconds of rest after each trial to prevent fatigue The raw data were stored on a personal computer for analysis with a custom program in Matlab Math Works Natick Massachusetts USA Investigators used a mean of data in three trials for analysis
Statistical Analysis
Data management and analysis were conducted using the statistical package for social studies SPSS version 22 for windows IBM SPSS Chicago IL USA Normal distribution of the data was tested using the Shapiro-Wilk test The homogeneity of variances between groups was examined using Levenes test Descriptive data are expressed as mean standard deviation An independent t-test was conducted for comparison of subject characteristics age body mass index BMI weight and height between both groups A univariate test of one way MANOVA was performed to compare EMG onset of each muscle between both groups Post-hoc analysis using the Bonferroni method was carried out for subsequent multiple comparison The level of significance for all statistical tests was set at p 005
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None