Ignite Creation Date:
2024-05-06 @ 3:16 PM
Last Modification Date:
2024-10-26 @ 1:46 PM
Study NCT ID:
NCT04572802
Status:
COMPLETED
Last Update Posted:
2022-04-20
First Post:
2020-09-29
Brief Title:
Changes of Serum Orphanin FQ in Patients With Coronary Heart Disease in Different Courses of Diabetes Mellitus
Sponsor:
Second Hospital of Shanxi Medical University
Organization:
Second Hospital of Shanxi Medical University
Study Overview
Official Title:
Study on the Changes of Serum Orphanin FQ in Patients With Diabetes Mellitus and Coronary Heart Disease in Different Courses
Status:
COMPLETED
Status Verified Date:
2022-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To explore the severity of diabetic patients with coronary heart disease and the change of serum orphanin FQ content in different diabetic courses
Detailed Description:
Methods A retrospective case-control study was conducted The control group was a patient who underwent coronary angiography at the same time and was definitely diagnosed as coronary heart disease but not diabetes The study group was coronary heart disease complicated with diabetes which was divided into group A 5 years group B 5-10 years and group C 10-20 years according to the course of diabetes 1 Review the electronic medical records and record the general information of the selected patients age sex history of hypertension history of myocardial infarction family history of coronary heart disease smoking history chronic kidney disease ② laboratory findings HbA1C glycosylated hemoglobin SBP systolic blood pressure DBP diastolic blood pressure total cholesterol HDL LDL triglyceride BMI creatinine and glomerular passing rate EGFR ③ Drug use oral hypoglycemic agents insulin aspirin statins hypertension drugs ACEI or ARB β-blockers CCB and diuretics ii Taking coronary angiography as the gold standard the grading index of severity of coronary heart disease was made and the severity of coronary heart disease was evaluated by Gensini score
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None