Ignite Creation Date:
2024-05-06 @ 3:16 PM
Last Modification Date:
2024-10-26 @ 1:46 PM
Study NCT ID:
NCT04576884
Status:
COMPLETED
Last Update Posted:
2020-10-06
First Post:
2020-09-21
Brief Title:
Age-Related Changes and Cycloplegia-Induced Differences in the Human Crystalline Lens
Sponsor:
Wenzhou Medical University
Organization:
Wenzhou Medical University
Study Overview
Official Title:
Age-Related Changes and Cycloplegia-Induced Differences of the Human Crystalline Lens Schlemm s Canal and Trabecular Meshworkan in Vivo Swept-Source Optical Coherence Tomography Study
Status:
COMPLETED
Status Verified Date:
2020-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The ocular biometric parameters of the human crystalline lens including anterior chamber depth ACD lens thickness LT radii of curvature of anterior and posterior lens ALR and PLR lens equatorial diameter LED and lens vault LV automatically quantified by the CASIA2 SS-OCT Tomey Nagoya Japan Images of iridocorneal angle were obtained using CASIA2 and the Schlemm s canal SC and trabecular meshwork TM were quantified manually Both cycloplegia and non-cycloplegia images were obtained
Detailed Description:
Healthy individuals aged between 6 and 90 years without history of ocular disease except age-related cataract andor myopia were consecutively included from April to May 2019 All participants underwent visual acuity dry and wet refraction anterior and posterior segment examination intraocular pressure IOP and axial length AL using IOL-Master 700 Carl Zeiss Meditec AG Investigators recruited children under 18 years old at a refraction outpatient clinic who were prescribed cyclopentolate hydrochloride eyedrops SA Alcon-Couvreur NV Belguim for cycloplegic refraction For adults they were prescribed compound tropicamide eyedrops Mydrin-P Santen Pharmaceutical Co Ltd Osaka Japan consisting of 05 tropicamide mixed with 05 phenylephrine hydrochloride for pupillary dilation in order to perform fundus examination at an outpatient clinic Exclusion criteria were as followocular diseases other than cataracts history of eye surgeries or injuries shallow anterior chamber with a risk of angle closure The data from right eye was selected for analysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None