Ignite Creation Date:
2024-05-05 @ 5:13 PM
Last Modification Date:
2024-10-26 @ 9:29 AM
Study NCT ID:
NCT00411320
Status:
COMPLETED
Last Update Posted:
2011-08-04
First Post:
2006-12-12
Brief Title:
Determinants of Corticosteroid Insensitivity in Smokers With Asthma
Sponsor:
University of Glasgow
Organization:
University of Glasgow
Study Overview
Official Title:
Determinants of Corticosteroid Insensitivity in Smokers With Asthma
Status:
COMPLETED
Status Verified Date:
2008-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Smokers with asthma display a relative insensitivity to inhaled and oral corticosteroids The causes of this phenomenon are currently unknown The investigators will perform a number of blood breathing tests to try to discover the causes behind this phenomenon with the aim of producing leads for further investigation and possible new treatments for smokers with asthma
Detailed Description:
Smokers with asthma display a relative insensitivity to inhaled and oral corticosteroids The causes of this phenomenon are currently unknown However research into steroid resistance in severe asthma and the smoking related condition chronic obstructive pulmonary disease COPD points to a number of possible causes We will characterise a group of smokers with asthma and perform a number of investigations and compare the results to ex-smokers and never smokers with asthma with the aim of establishing which previously published steroid resistance phenomena are related to the steroid resistance displayed by smokers with asthma Results produced from this trial will provide hypothesis generating information leading to future pharmaceutical trials
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None