Ignite Creation Date:
2024-05-06 @ 3:14 PM
Last Modification Date:
2024-10-26 @ 1:45 PM
Study NCT ID:
NCT04566900
Status:
RECRUITING
Last Update Posted:
2023-09-25
First Post:
2020-09-17
Brief Title:
Neurofeedback to Improve Working Memory in Mild Cognitive Impairment
Sponsor:
University of California San Diego
Organization:
University of California San Diego
Study Overview
Official Title:
Enhancing Gamma Band Response in Mild Cognitive Impairment to Improve Working Memory
Status:
RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Mild cognitive impairment MCI has been identified as an early phase of Alzheimers disease AD a neurodegenerative disorder expected to affect 139 million Americans by 2060 AD causes a progressive cognitive decline including problems related to learning and memory that adversely affects life quality Treatment intervention at the MCI stage of the disease could potentially slow down the rate at which people may convert from MCI to AD Increasing evidence suggests that abnormal activity in frontal regions of the brain is associated with cognitive deficits observed in AD Furthermore previous research has shown that neurofeedback NFB training targeting these regions can improve memory making it a potential treatment for AD NFB is a technique where an individual learns to change hisher brain function in a particular direction once that function has been made accessible through a visual or auditory metaphor We are proposing a novel computer-based brain-training program to enhance frontal gamma oscillatory activity in individuals with MCI Results from this study will build the scientific foundation necessary for larger clinical trials dedicated to improving treatment options and outcomes for patients with MCI
Detailed Description:
This is a randomized double-blind clinical trial to test the efficacy of gamma-neurofeedback G-NFB compared to a placebo P-NFB in individuals with MCI 112 consented participants will be randomized to receive G-NFB n56 or placebo-NFB n56 during 30-45 minute sessions twice per week for 12 weeks 24 total sessions Memory and other cognitive domains will be measured using paper and pencil and computerized tests every 4 weeks during the study and at 4 weeks post completion of study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None