Ignite Creation Date:
2024-05-05 @ 11:19 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001881
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Clinical Manifestations of Mutations in Genes Linked to Familial Cardiomyopathy
Status:
COMPLETED
Status Verified Date:
2000-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Genetically inherited heart diseases familial cardiomyopathies are conditions affecting the heart passed on to family members through abnormalities in genetic information These conditions are responsible for many heart related deaths and illnesses
In this study researchers hope to determine the signs and symptoms clinical correlation associated with specific genetic abnormalities causing inherited heart diseases
In order to do this researchers plan to evaluate patients and family members of patients diagnosed with inherited heart disease Patients participating in the study will undergo several tests including blood tests electrocardiograms EKG and echocardiograms Patients may also be asked to undergo an MRI of the heart to provide a clearer picture of it
Patients participating in this study may not be directly benefited by it However information gathered from the study may contribute to the medical care treatment and prevention of problems for others in the future
In this study researchers hope to determine the signs and symptoms clinical correlation associated with specific genetic abnormalities causing inherited heart diseases
In order to do this researchers plan to evaluate patients and family members of patients diagnosed with inherited heart disease Patients participating in the study will undergo several tests including blood tests electrocardiograms EKG and echocardiograms Patients may also be asked to undergo an MRI of the heart to provide a clearer picture of it
Patients participating in this study may not be directly benefited by it However information gathered from the study may contribute to the medical care treatment and prevention of problems for others in the future
Detailed Description:
Familial cardiomyopathy FC often demonstrates both non-allelic and allelic genetic heterogeneity We propose to determine the clinical correlates of specific genetic defects which cause FC by identifying and expanding a set of kindreds with identical and distinct molecular defects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 99-H-0065 | None | None | None |