Ignite Creation Date:
2024-05-06 @ 3:12 PM
Last Modification Date:
2024-10-26 @ 1:45 PM
Study NCT ID:
NCT04553900
Status:
COMPLETED
Last Update Posted:
2020-09-21
First Post:
2020-09-11
Brief Title:
Effect of Heat Stress on Global LV Function in Anesthetized Humans
Sponsor:
University of California San Diego
Organization:
University of California San Diego
Study Overview
Official Title:
Effect of Heat Stress on Global LV Function in Anesthetized Humans
Status:
COMPLETED
Status Verified Date:
2020-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Recent data suggests that increased temperature improves inotropic function during systole and may improve diastolic function in healthy humans at rest despite a reduction in left ventricular volume at end diastole The effect of heat stress has not been reported in patients receiving general anesthesia and the impact of general anesthesia on these findings is not known Trans-esophageal echocardiography will be used to measure parameters important to both systolic and diastolic function at temperature intervals of 1C in patients undergoing Heated Intraoperative Peritoneal Chemotherapy HIPEC That general anesthesia will not alter the cardiovascular effects of increased temperature that has been reported in healthy un-anesthetized humans is the hypothesis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None