Ignite Creation Date:
2024-05-06 @ 3:11 PM
Last Modification Date:
2024-10-26 @ 1:44 PM
Study NCT ID:
NCT04552262
Status:
TERMINATED
Last Update Posted:
2022-08-23
First Post:
2020-09-11
Brief Title:
Study to Learn More About the Effect of a New Drug Called BAY2327949 on the Blood Flow Through Kidneys in Adult Participants With Moderate Chronic Kidney Disease
Sponsor:
Bayer
Organization:
Bayer
Study Overview
Official Title:
A Randomized 2-way Crossover Placebo-controlled Double-blind Study to Evaluate Effects of Single Oral Doses of BAY 2327949 on Renal Perfusion in Participants With Moderate Chronic Kidney Disease
Status:
TERMINATED
Status Verified Date:
2022-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Terminated
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Researchers in this study want to learn more about the effect of a new drug called BAY2327949 on the blood flow through kidneys in adult participants with moderate long lasting kidney disease It is thought that in long lasting kidney disease blood flow through the kidney tissue is changed and that some parts of the kidney may receive less oxygen and nutrients because of this BAY2327949 is a new drug under development with a goal to modify how much blood is flowing through kidneys It works by binding to and blocking proteins that can regulate blood flow through the kidneys
Participants in this study will receive 3 tablets of BAY2327949 once and 3 tablets of Placebo once a placebo looks like a drug but does not have any medicine in it Both BAY2327949 and Placebo will be taken orally And after taking each of them participants will undergo a Magnetic Resonance Imaging MRI scanning for 60 to 90 minutes to assess the blood flow to kidneys MRI is an examination of parts of the body in this case the kidney which provides images of these regions Blood samples will be collected from the participants to check the general health and look at how the study drug is working in the body and how the body affects the study drug Participants will visit the hospital or clinic about 4 times in total and the observation for each participant will not more than 56 days
Participants in this study will receive 3 tablets of BAY2327949 once and 3 tablets of Placebo once a placebo looks like a drug but does not have any medicine in it Both BAY2327949 and Placebo will be taken orally And after taking each of them participants will undergo a Magnetic Resonance Imaging MRI scanning for 60 to 90 minutes to assess the blood flow to kidneys MRI is an examination of parts of the body in this case the kidney which provides images of these regions Blood samples will be collected from the participants to check the general health and look at how the study drug is working in the body and how the body affects the study drug Participants will visit the hospital or clinic about 4 times in total and the observation for each participant will not more than 56 days
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2019-003569-17 | EUDRACT_NUMBER | None | None |