Ignite Creation Date:
2024-05-06 @ 3:10 PM
Last Modification Date:
2024-10-26 @ 1:44 PM
Study NCT ID:
NCT04549064
Status:
UNKNOWN
Last Update Posted:
2021-08-23
First Post:
2020-09-09
Brief Title:
Biomarkers of Pancreatic Cancer and New Way to Detection
Sponsor:
First Affiliated Hospital Xian Jiaotong University
Organization:
First Affiliated Hospital Xian Jiaotong University
Study Overview
Official Title:
Identification of AREG for the Detection of Pancreatic Cancer By Biosensor
Status:
UNKNOWN
Status Verified Date:
2021-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Amphoteric regulatory protein AREG a member of epidermal growth factor EGF family is expressed in many tumorsOur study confirmed that the expression of AREG in the serum of patients with pancreatic cancer is significantly higher than that of patients with benign pancreatic diseases and healthy people which is expected to become a new early serum marker of pancreatic cancer The serum concentration of AREG was detected by traditional ELISA and compared with CA-199 which was a conventional tumor marker of pancreatic cancer Next we compare the advantages of using sensor to detect AREG compared with ELISA
Detailed Description:
Serum was collected pancreatic cancer healthy control 200200 Clinical data were collected age gender diagnosis cancer stage CA199 level at initial diagnosis histopathological type etc The informed consent of the subjects was obtained before the study and all experimental procedures were approved by ethics
Draw a summary table of patient characteristics The level of AREG was detected by ELISA kit and compared with CA199
Fabrication of a new electrochemical biosensor Characterization of sensor performance
Draw a summary table of patient characteristics The level of AREG was detected by ELISA kit and compared with CA199
Fabrication of a new electrochemical biosensor Characterization of sensor performance
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None