Ignite Creation Date:
2024-05-06 @ 3:09 PM
Last Modification Date:
2024-10-26 @ 1:44 PM
Study NCT ID:
NCT04546451
Status:
COMPLETED
Last Update Posted:
2023-06-01
First Post:
2020-08-29
Brief Title:
Countervail Cognitive and Cerebral Decline in Mild Cognitive Impairment Patients Using Non-medical Interventions
Sponsor:
School of Health Sciences Geneva
Organization:
School of Health Sciences Geneva
Study Overview
Official Title:
Musical and Psychomotor Interventions for Cognitive Sensorimotor and Cerebral Decline in Patients With Mild Cognitive Impairment COPE a Study Protocol for a Multicentric Randomized Controlled Study
Status:
COMPLETED
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COPE
Brief Summary:
Cognitive decline represents a major threat among the deleterious effects of population aging The investigators propose to conduct an RCT randomized controlled trial on the subpopulation of MCI patients and examine whether intensive musical or psychomotor group interventions can improve their cognitive and sensorimotor functioning as well as induce brain plasticity compared to a passive healthy control group matched for age gender and education level The 2 training regimens will take place twice a week over 6 months and will be provided by professionals in each field
Detailed Description:
Background Regular cognitive training can boost or maintain cognitive and brain functions known to decline with age Most studies administered such cognitive training on a computer and in a lab setting However everyday life activities like musical practice or physical exercise that are complex and variable could be more successful at inducing transfer effects to different cognitive domains and maintaining motivation Body-mind exercises like Tai Chi or psychomotor exercise may also positively affect cognitive functioning in the elderly We will investigate the influence of active music practice and psychomotor training over 6 months in Mild Cognitive Impairment patients from university hospital memory clinics on cognitive and sensorimotor performance and brain plasticity
Methods We aim to conduct a randomized controlled RCT multicenter intervention study on 32 Mild Cognitive Impairment MCI patients 60-80 years divided over 2 experimental groups 1 Music practice 2 Psychomotor treatment Controls will consist of a passive test-retest group of 16 age gender and education level matched healthy volunteers
The training regimens take place twice a week for 45 minutes over 6 months in small groups provided by professionals and patients should exercise daily at home Data collection takes place at baseline before the interventions 3 and 6 months after training onset on cognitive and sensorimotor capacities subjective well-being daily living activities and via functional and structural neuroimaging Considering the current constraints of the ongoing COVID-19 COronaVIrus Disease of 2019 pandemic recruitment and data collection takes place in 2 waves
Discussion We will investigate whether musical practice or psychomotor exercise in small groups can improve cognitive sensorimotor and brain functioning in MCI patients and therefore provoke benefits for their daily life functioning and well-being
Methods We aim to conduct a randomized controlled RCT multicenter intervention study on 32 Mild Cognitive Impairment MCI patients 60-80 years divided over 2 experimental groups 1 Music practice 2 Psychomotor treatment Controls will consist of a passive test-retest group of 16 age gender and education level matched healthy volunteers
The training regimens take place twice a week for 45 minutes over 6 months in small groups provided by professionals and patients should exercise daily at home Data collection takes place at baseline before the interventions 3 and 6 months after training onset on cognitive and sensorimotor capacities subjective well-being daily living activities and via functional and structural neuroimaging Considering the current constraints of the ongoing COVID-19 COronaVIrus Disease of 2019 pandemic recruitment and data collection takes place in 2 waves
Discussion We will investigate whether musical practice or psychomotor exercise in small groups can improve cognitive sensorimotor and brain functioning in MCI patients and therefore provoke benefits for their daily life functioning and well-being
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None