Ignite Creation Date:
2024-05-05 @ 5:12 PM
Last Modification Date:
2024-10-26 @ 9:29 AM
Study NCT ID:
NCT00406198
Status:
COMPLETED
Last Update Posted:
2006-12-04
First Post:
2006-11-30
Brief Title:
Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis
Sponsor:
Hopital Lariboisière
Organization:
Hopital Lariboisière
Study Overview
Official Title:
Phase 4 Randomized Multicentric Controlled Study on Impact of Continuous Venovenous Hemofiltration on Organ Failure at the Early Phase of Severe Sepsis
Status:
COMPLETED
Status Verified Date:
2006-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The impact of continuous veno-venous haemofiltration CVVH on sepsis-induced multiple organ failure severity is controversial We thus sought to assess the effect of early application of haemofiltration on the degree of organ dysfunction and plasma cytokine levels in patients with severe sepsis or septic shock
Detailed Description:
prospective randomized open multicentre study was performed between 1997 and 1999 in 16 French intensive care units Patients were enrolled within 24 hours of development of the first organ failure related to a new septic insult They were randomized to group 1 HF who received haemofiltration for a 96 hr period or group 2 C who were managed conventionally The primary end-point was the number severity and duration of organ failures at 14 days as evaluated by the SOFA score on an intention-to-treat analysis Strict guidelines were provided to perform continuous haemofiltration under the same conditions and objectives in all centres
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| ministère recherche EA 322 | None | None | None |