Ignite Creation Date:
2024-05-06 @ 3:07 PM
Last Modification Date:
2024-10-26 @ 1:43 PM
Study NCT ID:
NCT04529590
Status:
COMPLETED
Last Update Posted:
2024-02-01
First Post:
2020-08-24
Brief Title:
Precise Treatment of Prediabetes and Stage 1 Hypertension
Sponsor:
Ruijin Hospital
Organization:
Ruijin Hospital
Study Overview
Official Title:
Precise Treatment of Prediabetes and Stage 1 Hypertension
Status:
COMPLETED
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To identify the occurrence of diabetes hypertension cardiovascular and cerebrovascular events and all-cause death in patients with baseline prediabetes and stage1 hypertension after 18 years follow up To identify whether one or several metabolites can be used as serum markers to judge the prognosis of patients with prediabetes and stage1 hypertension and to establish the evaluation model of metabolites for the prognosis
Detailed Description:
To identify the occurrence of diabetes hypertension cardiovascular and cerebrovascular events and all-cause death in patients with baseline prediabetes and stage1 hypertension after18 years follow up then explore the role of risk factors After assessing the association between BP categories and all-cause mortality and cardiovascular mortality to analyze the risk for all-cause and cardiovascular mortality by blood glucose categories and BP categories combined by using multiple Cox regression analysis To analyze the corresponding incidence of all-cause mortality per 1000 person-years for the BP13080 mmHg 130-13980-89 mmHg and 14090 mmHg or treated groups respectively after adjusting for age sex and other factors To identify the associations between cardiovascular mortality and BP categories alone or combined with blood glucose categories were consistent with that of all-cause mortality
To identify relative metabolic molecular biomarker panel detected by mass spectrometry in blood samples correlating with efficacy in prediabetes and stage 1 hypertension among Chinese adults Compare the plasma metabolic profiles of different groups and the metabolic markers were screened and optimized by multivariate statistical analysis logistic regression analysis and receiver operating characteristic ROC curve analysis
To determine whether one or several metabolites can be used as serum markers to judge the prognosis of patients with prediabetes and stage1 hypertension and to establish the evaluation model of metabolites for the prognosis
To identify relative metabolic molecular biomarker panel detected by mass spectrometry in blood samples correlating with efficacy in prediabetes and stage 1 hypertension among Chinese adults Compare the plasma metabolic profiles of different groups and the metabolic markers were screened and optimized by multivariate statistical analysis logistic regression analysis and receiver operating characteristic ROC curve analysis
To determine whether one or several metabolites can be used as serum markers to judge the prognosis of patients with prediabetes and stage1 hypertension and to establish the evaluation model of metabolites for the prognosis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None