Ignite Creation Date:
2024-05-06 @ 3:05 PM
Last Modification Date:
2024-10-26 @ 1:42 PM
Study NCT ID:
NCT04518254
Status:
COMPLETED
Last Update Posted:
2022-11-25
First Post:
2020-08-15
Brief Title:
Contribution of L-Tyrosine to Human Decision Making in Stressful Situations
Sponsor:
Direction Centrale du Service de Santé des Armées
Organization:
Direction Centrale du Service de Santé des Armées
Study Overview
Official Title:
Contribution of L-Tyrosine to Human Decision Making in Stressful Situations
Status:
COMPLETED
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TYRO-STRESS
Brief Summary:
L-tyrosine is a chemical precursor of dopamine Under specific conditions tyrosine administration can increase brain dopamine levels and therefore several studies have explored whether tyrosine supplementation can have a beneficial effect on cognitive and behavioural performance that is dependent on dopaminergic function However the effects of tyrosine supplementation are mixed some studies show positive effects while others do not Stress leads to an increase in dopaminergic activity and turnover in the brain resulting in a decrease in brain dopamine levels We propose to study the contribution of tyrosine to decision making and more particularly to the processes of response selection mediated by the prefrontal cortex and under the influence of the dopaminergic system in stressful situations
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2019-A03194-53 | OTHER | IDRCB | None |