Ignite Creation Date:
2024-05-06 @ 3:04 PM
Last Modification Date:
2024-10-26 @ 1:42 PM
Study NCT ID:
NCT04513964
Status:
WITHDRAWN
Last Update Posted:
2022-04-07
First Post:
2020-08-13
Brief Title:
Impact of COVID-19 on the Benefit of Cardiac Rehabilitation
Sponsor:
Fondation Hôpital Saint-Joseph
Organization:
Fondation Hôpital Saint-Joseph
Study Overview
Official Title:
Impact of COVID-19 on the Benefit of Cardiac Rehabilitation
Status:
WITHDRAWN
Status Verified Date:
2022-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
The project was abandoned
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
REACARDIOCOVID
Brief Summary:
The COVID-19 attack is polymorphic with otorhinolaryngological pneumological cardiac digestive neurological muscular attacks with a higher mortality in subjects with comorbidity 70 years old cardiovascular history in particular Arterial hypertension hypertension heart disease This polymorphism is linked to vasculitis and the immune response
Patients with cardiovascular disease are particularly at risk of decompensating particularly due to the increased metabolism induced by viral infection and reduced cardiovascular capacities
On the cardiovascular level two sides can be considered On the one hand cardiovascular disease hypertension coronary artery disease is a comorbid factor On the other hand the myocardial damage reflected by the increase in troponin or an alteration of the ejection fraction is a very clear risk factor for death or severe form
Cardiovascular involvement is particularly high in hospitalized and deceased patients The odds ratio calculated in a meta-analysis of severe forms of covid-19 with hypertension is 3 19 31 for cardiovascular pathologies of 293 173 496 Recommendations were made for pulmonary rehabilitation but not for cardiovascular rehabilitation
Cardiac rehabilitation is indicated in most cardiovascular pathologies after acute coronary syndrome after coronary angioplasty in heart failure after coronary or valve heart surgery etc
It consists of a multidisciplinary approach combining therapeutic pharmacological adjustment physical activity therapeutic education in order to improve physical capacities for exertion and reduce morbidity and mortality The physical exercises can be endurance or resistance type
Capacity gain at the end of rehabilitation is measured by visual scales quality of life questionnaires and a stress test at the start and end of rehabilitation Most often rehabilitation centers only do the stress test and estimate through questioning for subjective improvement
The hypothesis is that patients who contracted COVID-19 would have lower cardiac capacities after recovery from the infection than patients without COVID-19 or that their capacity for recovery would be less There could be a difference in recovery after cardiac rehabilitation between the two populations regardless of whether the cardiac damage requiring rehabilitation was triggered by COVID-19 or was pre-existing
Patients with cardiovascular disease are particularly at risk of decompensating particularly due to the increased metabolism induced by viral infection and reduced cardiovascular capacities
On the cardiovascular level two sides can be considered On the one hand cardiovascular disease hypertension coronary artery disease is a comorbid factor On the other hand the myocardial damage reflected by the increase in troponin or an alteration of the ejection fraction is a very clear risk factor for death or severe form
Cardiovascular involvement is particularly high in hospitalized and deceased patients The odds ratio calculated in a meta-analysis of severe forms of covid-19 with hypertension is 3 19 31 for cardiovascular pathologies of 293 173 496 Recommendations were made for pulmonary rehabilitation but not for cardiovascular rehabilitation
Cardiac rehabilitation is indicated in most cardiovascular pathologies after acute coronary syndrome after coronary angioplasty in heart failure after coronary or valve heart surgery etc
It consists of a multidisciplinary approach combining therapeutic pharmacological adjustment physical activity therapeutic education in order to improve physical capacities for exertion and reduce morbidity and mortality The physical exercises can be endurance or resistance type
Capacity gain at the end of rehabilitation is measured by visual scales quality of life questionnaires and a stress test at the start and end of rehabilitation Most often rehabilitation centers only do the stress test and estimate through questioning for subjective improvement
The hypothesis is that patients who contracted COVID-19 would have lower cardiac capacities after recovery from the infection than patients without COVID-19 or that their capacity for recovery would be less There could be a difference in recovery after cardiac rehabilitation between the two populations regardless of whether the cardiac damage requiring rehabilitation was triggered by COVID-19 or was pre-existing
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None