Ignite Creation Date:
2024-05-06 @ 3:03 PM
Last Modification Date:
2024-10-26 @ 1:41 PM
Study NCT ID:
NCT04502940
Status:
COMPLETED
Last Update Posted:
2021-05-03
First Post:
2020-08-04
Brief Title:
Is Lymphocyte Subtype Important for Acute Pancreatitis Severity
Sponsor:
Istanbul Training and Research Hospital
Organization:
Istanbul Training and Research Hospital
Study Overview
Official Title:
Can we Measure Pancreatitis Severity With Flow Cytometry
Status:
COMPLETED
Status Verified Date:
2021-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Pancreatitis is a common complication especially in patients with gallbladder stones most patients with biliary pancreatitis may recover spontaneously without sequelae but in 10-20 of patients the disease is severe and mortality rates of up to 30 are detected in these patients In the evaluation of acute biliary pancreatitis many scoring systems have been established Atlanta Ranson APACHE BISAP etc from past to present to determine morbidity and mortality of the disease
In this study the investigators aimed to evaluate the correlation between morbidity and mortality of acute biliary pancreatitis and lymphocyte subtypes with Flow-cytometry
In this study the investigators aimed to evaluate the correlation between morbidity and mortality of acute biliary pancreatitis and lymphocyte subtypes with Flow-cytometry
Detailed Description:
Pancreatitis is a common complication especially in patients with gallbladder stones most patients with biliary pancreatitis may recover spontaneously without sequelae but in 10-20 of patients the disease is severe and mortality rates of up to 30 are detected in these patients In patients with severe pancreatitis aggressive fluid replacement organ damage follow-up appropriate antibiotherapy and endoscopic sphincterotomy and radiological interventions may be of great benefit In the evaluation of acute biliary pancreatitis many scoring systems have been established Atlanta Ranson APACHE BISAP etc from past to present to determine morbidity and mortality of the disease There are limited number of studies in the literature about the immune parameters in the evaluation of acute pancreatitis In a studies serum inflammatory markers such as IL-1 IL-6 and CD4 CD8 T lymphocyte and Treg population were evaluatedTreg cells are reported to be an independent prognostic factor in determining the severity of acute pancreatitis In patients diagnosed with acute biliary pancreatitis determination of the course of the disease at the time of diagnosis is extremely important for treatment and survival
In this study the investigators aimed to evaluate the correlation between morbidity and mortality of acute biliary pancreatitis with lymphocyte subtypes via Flow-cytometry
In this study the investigators aimed to evaluate the correlation between morbidity and mortality of acute biliary pancreatitis with lymphocyte subtypes via Flow-cytometry
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None