Ignite Creation Date:
2024-05-06 @ 3:03 PM
Last Modification Date:
2024-10-26 @ 1:42 PM
Study NCT ID:
NCT04505800
Status:
COMPLETED
Last Update Posted:
2021-03-22
First Post:
2020-06-23
Brief Title:
Tryptophan Supplementation to Improve Night Shift Workers Health
Sponsor:
National Yang Ming Chiao Tung University
Organization:
National Yang Ming Chiao Tung University
Study Overview
Official Title:
Chrononutrition of Using L-tryptophan Supplementation to Alleviate the Impacts of Night Shift Rotation on Circadian Hormones and Health Outcomes
Status:
COMPLETED
Status Verified Date:
2021-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This randomized cross-over double-blinded trial aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work and to examine the influences of different frequencies and timings of supplementation on the health effects
Detailed Description:
This study aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work and to examine the influences of different frequencies and timings of supplementation on the health effects Night shift work affects melatonin and cortisol variation insomnia mood issues and metabolic syndrome Short-term tryptophan supplementation was shown to improve melatonin sleep quality and cortisol response to acute stress Little is known whether a longer term of longer-term tryptophan supplementation would alleviate the health impacts of night shift work Nevertheless melatonin and cortisol have their normal circadian patterns Nothing is known about what temporal structure of tryptophan supplement would maximize its health effects on night shift workers melatonin and cortisol levels We will conduct a double-blind cross-over randomized controlled trial to examine the benefits of oral tryptophan administration 3gday tid on night shift workers health outcomes melatonin and cortisol levels sleep quality moods and work performance We expect to reveal the health effect of tryptophan supplementation in night shift workers by using sophisticated study design
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None