Ignite Creation Date:
2024-05-06 @ 3:03 PM
Last Modification Date:
2024-10-26 @ 1:42 PM
Study NCT ID:
NCT04506021
Status:
UNKNOWN
Last Update Posted:
2020-08-10
First Post:
2020-08-03
Brief Title:
A Real World Study on Clinical Efficacy of Bicarbonate Ringers Solution in Biliary Atresia Children
Sponsor:
Tongji Hospital
Organization:
Tongji Hospital
Study Overview
Official Title:
A Multicenter Real World Study on Clinical Efficacy of Sodium Bicarbonate Ringers Solution in Children With Biliary Atresia
Status:
UNKNOWN
Status Verified Date:
2020-08
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In most babies with biliary atresia BA bile ducts on the inside and outside of the liver are affected eventually leading to a complete blockage of bile flow from the liver This in turn causes scarring fibrosis in the liver The surgery called the Kasai procedure and eventually a liver transplant could treat biliary atresia However children with BA have poor liver function poor renal reserve and poor ability to regulate water and electrolytes Therefore A reasonable and effective perioperative fluid management is more significant Considering the high chlorine of saline the liver burden of Lactated Ringers solution and Acetated Ringers solution the Bicarbonate Ringers solution which composition is similar to plasma could be the best choice for perioperative fluid management of BA children Therefore we hypothesize that compared with other crystalloids Bicarbonate Ringers solution is a better choice to maintain water electrolyte and acid-base balance in BA children
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None