Ignite Creation Date:
2024-05-05 @ 9:42 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005540
Status:
COMPLETED
Last Update Posted:
2017-03-31
First Post:
2000-05-25
Brief Title:
Physical Fitness and Cardiovascular Mortality in Firefighters
Sponsor:
University of Southern California
Organization:
University of Southern California
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2017-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To study prospectively the interrelationships among physical fitness activity other measured risk factors coronary heart disease CHD and all-cause mortality in a cohort of 3403 firefighters
Detailed Description:
BACKGROUND
From 1971-1991 the Occupational Health Service of Los Angeles Country measured physical fitness and other CHD risk factors including physical activity anthropometric measures blood pressure smoking family history of CHD and levels of total cholesterol uric acid and glucose in Los Angeles County firefighters at application and routine intervals approximately every three years The entire cohort of 3403 firefighters is now followed for mortality up to 1996
DESIGN NARRATIVE
The entire cohort of 3403 firefighers is followed up to 1996 in this longitudinal study The investigators are using a variety of tracing sources including the National Death Index and obtaining death certificates to determine date and cause of death Cohort data will be analyzed to address the following aims 1 To provide a longitudinal description of and determine the interrelationships among physical fitness physical activity and other measured risk factors 2 to determine whether levels of physical fitness are related independently of other known and measured risk factors CHD and all-cause mortality 3 To determine whether there is a gradient of decreasing CHD risk with increasing levels of physical fitness or whether there appears to be some threshold of physical fitness above which CHD risk stabilizes 4 To determine whether the relationship between physical fitness and CHD and all-cause mortality varies by such cardiovascular risk factors as age cholesterol levels blood pressure smoking and obesity
From 1971-1991 the Occupational Health Service of Los Angeles Country measured physical fitness and other CHD risk factors including physical activity anthropometric measures blood pressure smoking family history of CHD and levels of total cholesterol uric acid and glucose in Los Angeles County firefighters at application and routine intervals approximately every three years The entire cohort of 3403 firefighters is now followed for mortality up to 1996
DESIGN NARRATIVE
The entire cohort of 3403 firefighers is followed up to 1996 in this longitudinal study The investigators are using a variety of tracing sources including the National Death Index and obtaining death certificates to determine date and cause of death Cohort data will be analyzed to address the following aims 1 To provide a longitudinal description of and determine the interrelationships among physical fitness physical activity and other measured risk factors 2 to determine whether levels of physical fitness are related independently of other known and measured risk factors CHD and all-cause mortality 3 To determine whether there is a gradient of decreasing CHD risk with increasing levels of physical fitness or whether there appears to be some threshold of physical fitness above which CHD risk stabilizes 4 To determine whether the relationship between physical fitness and CHD and all-cause mortality varies by such cardiovascular risk factors as age cholesterol levels blood pressure smoking and obesity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL058227 | NIH | None | httpsreporternihgovquickSearchR01HL058227 |