Ignite Creation Date:
2024-05-06 @ 2:59 PM
Last Modification Date:
2024-10-26 @ 1:41 PM
Study NCT ID:
NCT04499287
Status:
COMPLETED
Last Update Posted:
2021-07-23
First Post:
2020-07-31
Brief Title:
Mealtime Walking Study to Improve Postprandial Metabolic Response
Sponsor:
Arizona State University
Organization:
Arizona State University
Study Overview
Official Title:
Mealtime Walking Study to Improve Postprandial Metabolic Response
Status:
COMPLETED
Status Verified Date:
2021-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This randomized crossover trial will investigate the metabolic responses following the consumption of a bageljuice meal under 3 conditions control fiber positive control and postmeal walk in15 healthy adults It is hypothesized that the postmeal walk will reduce glycemia insulinemia and oxidative stress similar to fiber
Detailed Description:
The study will follow a randomized crossover design Participants and the investigator will be blinded for the control treatments but not for the walk treatment Participants will complete 3 meal tests tests are separated by about 1 week An initial screening visit will be scheduled for the online survey respondents that meet the inclusion criteria and are willing to consider participation At this visit written consent will be secured followed by further screening for the exclusion criteria and the collection of demographic and health history data and anthropometric measures A fasting blood sample will be collected for glucose analysis Participants will be scheduled for experimental testing and provided with instructions and calendars Participants will be given at least one weeks notice if they do not qualify for the trial based on fasting glucose concentrations
On the day prior to each experimental day the participants will consume 2 bagels 54 g carbohydratebagel and on the night prior to each visit participants will consume a standard dinner of their choice The bagels will be provided to participants and the standardized dinner will be documented The bagels and standardized dinner meal will facilitate controlled glycogen loading prior to testing No other food will be consumed after this dinner meal and participants will fast overnight until they arrive at the research center the next morning eg no food or beverage with the exception of water Fasting blood 1 tablespoon will be collected and the test meal bageljuice will be consumed Postprandial blood samples will be collected for 4 hours see below The subjects will not be allowed to consume any food or beverage with the exception of water through the duration the visit A snack will be provided to participants once the testing is over
Glucose 0153060120 180 240 Insulin 0 30 120 180 240 Oxidative Stress Markers 0 180 240
The blood insulin level will be determined in venous blood by RIA Capillary blood glucose will be determined with a glucometer Oxidative stress eg total antioxidant capacity IL-6 and TBARS will be assessed using microplate analyses kits
On the day prior to each experimental day the participants will consume 2 bagels 54 g carbohydratebagel and on the night prior to each visit participants will consume a standard dinner of their choice The bagels will be provided to participants and the standardized dinner will be documented The bagels and standardized dinner meal will facilitate controlled glycogen loading prior to testing No other food will be consumed after this dinner meal and participants will fast overnight until they arrive at the research center the next morning eg no food or beverage with the exception of water Fasting blood 1 tablespoon will be collected and the test meal bageljuice will be consumed Postprandial blood samples will be collected for 4 hours see below The subjects will not be allowed to consume any food or beverage with the exception of water through the duration the visit A snack will be provided to participants once the testing is over
Glucose 0153060120 180 240 Insulin 0 30 120 180 240 Oxidative Stress Markers 0 180 240
The blood insulin level will be determined in venous blood by RIA Capillary blood glucose will be determined with a glucometer Oxidative stress eg total antioxidant capacity IL-6 and TBARS will be assessed using microplate analyses kits
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None