Ignite Creation Date:
2024-05-06 @ 2:58 PM
Last Modification Date:
2024-10-26 @ 1:40 PM
Study NCT ID:
NCT04482907
Status:
COMPLETED
Last Update Posted:
2020-07-23
First Post:
2020-07-16
Brief Title:
Effect of Dill in Thyroiditis and Nodular Goiter Patients
Sponsor:
Bezmialem Vakif University
Organization:
Bezmialem Vakif University
Study Overview
Official Title:
Randomized Placebo Controlled Clinical Study of Anethum Graveolens L Dill in Thyroiditis and Nodular Goiter Patients
Status:
COMPLETED
Status Verified Date:
2020-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Dill
Brief Summary:
The aim of the study was to investigate the functional and morphological effects of Anethum graveolens L in patients with thyroiditis and nodular goiter by evaluating hormone levels anti-Inflammatory markers and comparing thyroid nodule sizes measured by ultrasonography for 90 days
The effect of Anethum graveolens L was evaluated in euthyroid goiter patients diagnosed with benign thyroid nodule via fine needle aspiration biopsy Aerial parts of Anethum graveolens L were dried and grinded to yield a fine powder Size 1 hydroxypropyl methylcellulose capsules were filled with 300 mg powder Placebo was prepared in the same manner using maltodextrin Patients were suggested to take 3 pills a day Blood samples were collected at the initial and the final day for thyroid stimulating hormone TSH free triiodothyronine fT3 free thyroxine fT4 anti-thyroid peroxidase anti-TPO anti-thyroglobulin Anti-Tg and C-reactive protein CRP analysis Nodule sizes were also measured at the beginning and at the end of the trial with ultrasonography to identify the changes and effectiveness of dill dosage forms
After 90 days in the study the status of TSH fT3 fT4 anti-TPO and CRP levels were examined in the group with and without Anethum graveolens L
Again after the study the size of thyroid nodules was evaluated in the group who received and did not receive Anethum graveolens L by ultrasonography
The effect of Anethum graveolens L was evaluated in euthyroid goiter patients diagnosed with benign thyroid nodule via fine needle aspiration biopsy Aerial parts of Anethum graveolens L were dried and grinded to yield a fine powder Size 1 hydroxypropyl methylcellulose capsules were filled with 300 mg powder Placebo was prepared in the same manner using maltodextrin Patients were suggested to take 3 pills a day Blood samples were collected at the initial and the final day for thyroid stimulating hormone TSH free triiodothyronine fT3 free thyroxine fT4 anti-thyroid peroxidase anti-TPO anti-thyroglobulin Anti-Tg and C-reactive protein CRP analysis Nodule sizes were also measured at the beginning and at the end of the trial with ultrasonography to identify the changes and effectiveness of dill dosage forms
After 90 days in the study the status of TSH fT3 fT4 anti-TPO and CRP levels were examined in the group with and without Anethum graveolens L
Again after the study the size of thyroid nodules was evaluated in the group who received and did not receive Anethum graveolens L by ultrasonography
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None