Ignite Creation Date:
2024-05-06 @ 2:57 PM
Last Modification Date:
2024-10-26 @ 1:40 PM
Study NCT ID:
NCT04478032
Status:
UNKNOWN
Last Update Posted:
2021-09-14
First Post:
2020-07-16
Brief Title:
Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia
Sponsor:
Shanghai Mental Health Center
Organization:
Shanghai Mental Health Center
Study Overview
Official Title:
Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia a Double-Blind Randomized Clinical Trial
Status:
UNKNOWN
Status Verified Date:
2021-07
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Based on the hypothesis that low-frequency deep transcranial magnetic stimulationdTMS on anterior cingulate cortex ACC could down-regulate the glutamate level of ACC and regulate the acc-related functional network in patients with treatment resistance schizophreniathis research plan to utilise multimodal functional magnetic imaging methodincluding structural MRIresting-state functional magnetic resonance imaging and 1H-MRS to investigate therapeutic efficacy of low-frequency deep transcranial magnetic stimulation on SZ patients symptomsas well as to elucidate the correlation between treatment effects and glutamate level of ACC
Detailed Description:
This study includes 20 treatment resistance schizophrenia patients and 20 healthy controlsThis study will investigate 1abnormalities of the glutamate level of ACC in patients with schizophrenia compared to healthy controls by using 1H-MRS technique 2potential modulation effects of deep transcranial magnetic stimulationdTMS on anterior cingulate cortex function of patients with schizophrenia 3the therapeutic efficacy of dTMS on cognitive impairments and other psychotic symptoms of patients with schizophrenia by adopting cognitive function and psychotic symptoms evaluationas well as to explore the optimal dTMS treatment pattern on cognitive function
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None