Ignite Creation Date:
2024-05-06 @ 2:51 PM
Last Modification Date:
2024-10-26 @ 1:38 PM
Study NCT ID:
NCT04442165
Status:
COMPLETED
Last Update Posted:
2023-10-05
First Post:
2020-06-16
Brief Title:
Characterising Transmission of SARS-CoV-2 in a Peri-urban Population in Mozambique
Sponsor:
Institute of Tropical Medicine Belgium
Organization:
Institute of Tropical Medicine Belgium
Study Overview
Official Title:
Characterising Transmission of SARS-CoV-2 in a Peri-urban Population in Mozambique Using Population-based SeroSurveillance
Status:
COMPLETED
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AfriCoVER
Brief Summary:
A population-based COVID19 surveillance in a household cohort will be set-up using an existing Household demographic surveillance system HDSS From any individual in this population with any respiratory symptom or loss of smell or taste with or without fever investigators will collect a respiratory specimen and test these for SARS-CoV-2 virus during 12 months Demographic epidemiological and clinical data of possible cases and of the source population will be recorded at baseline
An age-stratified serial sero-survey will be conducted at baseline in a subset of the population in the population-based COVID19 surveillance and at 3 6 and 12 months after confirmation of community transmission
An age-stratified serial sero-survey will be conducted at baseline in a subset of the population in the population-based COVID19 surveillance and at 3 6 and 12 months after confirmation of community transmission
Detailed Description:
The investigators will use the established HDSS to set up population-based COVID19 surveillance in a household cohort From any individual in this population with any respiratory symptom or loss of smell or taste with or without fever investigators will collect a respiratory specimen and test these for SARS-CoV-2 virus by PCR during 12 months These cases will be identified through bi-weekly household visits through an alert system involving community leaders and HDSS interviewers or when presenting with symptoms at healthcare centres or the referral hospital Demographic epidemiological and clinical data comorbidities medication obesity HIV TB smoking of possible cases and of the source population will be recorded at baseline recent illness potential risk exposure of each household member including duration and type to SARS-CoV-2 positive individuals uptake of measures to reduce exposuretransmission and barriers to the uptake of such measures will be recordedupdated during every household visit
An age-stratified serial sero-survey will be conducted at baseline in a subset of the population in the population-based COVID19 surveillance and at 3 6 and 12 months after confirmation of community transmission
An age-stratified serial sero-survey will be conducted at baseline in a subset of the population in the population-based COVID19 surveillance and at 3 6 and 12 months after confirmation of community transmission
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None