Ignite Creation Date:
2024-05-05 @ 5:09 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00395590
Status:
UNKNOWN
Last Update Posted:
2006-11-03
First Post:
2006-11-02
Brief Title:
Polymorphisms in Inflammatory Cytokines Genes in Subjects With Obstructive Sleep Apnea
Sponsor:
Shaare Zedek Medical Center
Organization:
Shaare Zedek Medical Center
Study Overview
Official Title:
A Cross Sectional Study of Patients With Obstructive Sleep Apnea for Polymorphisms in Genes of Inflammatory Cytokines
Status:
UNKNOWN
Status Verified Date:
2005-02
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Obstructive sleep apnea is a common sleep disorder It is known to be related with increased body mass abdominal obesity insulin resistance and hypertension It is currently believed to be a feature of the metabolic syndrome Other features of the metabolic syndrome-such as insulin resistace were found related to inflammation and inflammatory cytokines Several polymorphisms in the genes that encode interleukin 6inteleukin 10 and TNF-alpha have significant influence on the amounts of cytokine production we thus hypothesize that polymorphisms related to increased pruduction are more common in subjects with OSA than in matched controls
Detailed Description:
Patients attending a sleep apnea clinic for evluation will be recruited Patients found positive for OSA will be compared to the patients with a negative study for OSA for the prevalence of polymorphisms in genes of inflammatory cytokines and cytokine levels
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None