Ignite Creation Date:
2024-05-05 @ 11:19 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00004656
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
2000-02-24
Brief Title:
Nutritional Aspects of Rett Syndrome
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
Office of Rare Diseases ORD
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
1999-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
OBJECTIVES I Determine dietary macronutrient intake in children with Rett syndrome and in healthy controls
II Measure sleeping and awake metabolic rates in various positions ie reclining sitting and standing by whole-room indirect calorimetry and isotope dilution
III Quantify activity patterns by time-motion studies using 24-hour activity records and 12-hour videotaping
IV Correlate 24-hour activity patterns with 24-hour heart rate telemetry and short-term oxygen consumption
V Estimate 24-hour fecal and urinary energy losses VI Determine body composition by clinical anthropometry whole-body potassium counting and total-body electrical conductance
VII Calculate apparent energy needs based on measurement of energy intake and expenditure
II Measure sleeping and awake metabolic rates in various positions ie reclining sitting and standing by whole-room indirect calorimetry and isotope dilution
III Quantify activity patterns by time-motion studies using 24-hour activity records and 12-hour videotaping
IV Correlate 24-hour activity patterns with 24-hour heart rate telemetry and short-term oxygen consumption
V Estimate 24-hour fecal and urinary energy losses VI Determine body composition by clinical anthropometry whole-body potassium counting and total-body electrical conductance
VII Calculate apparent energy needs based on measurement of energy intake and expenditure
Detailed Description:
PROTOCOL OUTLINE
All participants undergo extensive nutritional and metabolic assessment with body composition evaluation Studies include macronutrient intake body fat lean muscle mass metabolic rate and time-action studies and 24-hour cardiac telemetry Rett syndrome girls also receive a hemogram and hand x-ray
All participants undergo extensive nutritional and metabolic assessment with body composition evaluation Studies include macronutrient intake body fat lean muscle mass metabolic rate and time-action studies and 24-hour cardiac telemetry Rett syndrome girls also receive a hemogram and hand x-ray
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| BCM-CNRC-H1637 | None | None | None |