Ignite Creation Date:
2024-05-05 @ 5:08 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00392964
Status:
COMPLETED
Last Update Posted:
2007-04-11
First Post:
2006-10-25
Brief Title:
Patterns of Antiacids Use in Patients With IHD Admitted to Department of Internal Medicine
Sponsor:
Rambam Health Care Campus
Organization:
Rambam Health Care Campus
Study Overview
Official Title:
Patterns of Antiacids Use in Patients With IHD Admitted to Department of Internal Medicine
Status:
COMPLETED
Status Verified Date:
2007-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There is substantial continuing and unexplained rise in prescribing of proton pump inhibitors It is unknown whether their use in practice has corresponded to their licensed indications
Although the indications for H2RA or PPI administration in the treatment of acid-related diseases and the prevention of gastric mucosal damage have been well defined in the medical literature the perception of benefit from their use frequently tends to be extrapolated to all patients in general leading to an excessive consumption of these drugs in general practice
To date however little has been published with regard to the overall use or misuse of these drugs in hospital populations in ischemic heart disease patients as a secondary prevention to Aspirin use
We will undertake a 6-months retrospective survey about 1200 patients to evaluate the use of acid-suppressive medications in the general internal medicine ward of Rambam Hospital
We will extract all records of prescribing of a proton pump inhibitor within Rambam Hospital computerized patients file program Premetheuos in period of half year categorized and analyze them using statistical X2 test
Although the indications for H2RA or PPI administration in the treatment of acid-related diseases and the prevention of gastric mucosal damage have been well defined in the medical literature the perception of benefit from their use frequently tends to be extrapolated to all patients in general leading to an excessive consumption of these drugs in general practice
To date however little has been published with regard to the overall use or misuse of these drugs in hospital populations in ischemic heart disease patients as a secondary prevention to Aspirin use
We will undertake a 6-months retrospective survey about 1200 patients to evaluate the use of acid-suppressive medications in the general internal medicine ward of Rambam Hospital
We will extract all records of prescribing of a proton pump inhibitor within Rambam Hospital computerized patients file program Premetheuos in period of half year categorized and analyze them using statistical X2 test
Detailed Description:
Dyspeptic symptoms are a common presenting complaint and there is continuing debate about management Acid suppressant drugs the most potent of which are proton pump inhibitors are often prescribed and it has been suggested that proton pump inhibitors are probably too widely prescribed for minor symptoms and the cost implications of this are clear There is substantial continuing and unexplained rise in prescribing of proton pump inhibitors It is unknown whether their use in practice has corresponded to their licensed indications
Although the indications for H2RA or proton pump inhibitor administration in the treatment of acid-related diseases and the prevention of gastric mucosal damage have been well defined in the medical literature the perception of benefit from their use frequently tends to be extrapolated to all patients in general leading to an excessive consumption of these drugs in general practice
In addition Physicians nowadays tend to prescribe proton pump inhibitors for cardiac patients who use aspirin as secondary prevention of their illness
To date however little has been published with regard to the overall use or misuse of these drugs in hospital populations or to the fall-out of hospital prescriptions in general practice and none has been published regarding its use in ischemic heart disease patients as a secondary prevention to Aspirin use
We will undertake a 6-months retrospective survey about 1200 patients to evaluate the use of acid-suppressive medications in the general internal medicine ward of Rambam Hospital a large teaching hospital in Northern Israel as well as the appropriateness of their prescription to the licensed indications while dividing them to subgroups of ischemic heart disease patients
We will extract all records of prescribing of a proton pump inhibitor within Rambam Hospital computerized patients file program Premetheuos in period of half year categorized and analyze them using statistical X2 test
Although the indications for H2RA or proton pump inhibitor administration in the treatment of acid-related diseases and the prevention of gastric mucosal damage have been well defined in the medical literature the perception of benefit from their use frequently tends to be extrapolated to all patients in general leading to an excessive consumption of these drugs in general practice
In addition Physicians nowadays tend to prescribe proton pump inhibitors for cardiac patients who use aspirin as secondary prevention of their illness
To date however little has been published with regard to the overall use or misuse of these drugs in hospital populations or to the fall-out of hospital prescriptions in general practice and none has been published regarding its use in ischemic heart disease patients as a secondary prevention to Aspirin use
We will undertake a 6-months retrospective survey about 1200 patients to evaluate the use of acid-suppressive medications in the general internal medicine ward of Rambam Hospital a large teaching hospital in Northern Israel as well as the appropriateness of their prescription to the licensed indications while dividing them to subgroups of ischemic heart disease patients
We will extract all records of prescribing of a proton pump inhibitor within Rambam Hospital computerized patients file program Premetheuos in period of half year categorized and analyze them using statistical X2 test
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None