Ignite Creation Date:
2024-05-06 @ 2:42 PM
Last Modification Date:
2024-10-26 @ 1:35 PM
Study NCT ID:
NCT04399447
Status:
UNKNOWN
Last Update Posted:
2020-05-22
First Post:
2020-05-09
Brief Title:
Multicenter Normal Reference Study of Tissue Motion Tracking of Mitral Annular DisplacementTMAD
Sponsor:
Weidong Ren
Organization:
Shengjing Hospital
Study Overview
Official Title:
The Multi-center Normal Reference Study of Tissue Motion Tracking of Mitral Annular DisplacementTMAD in Chinese Han Adults Study
Status:
UNKNOWN
Status Verified Date:
2020-05
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TMAD
Brief Summary:
To establish the range of TMADmidTMADmidpt by using tissue motion tracking of mitral annular displacement TMAD and to explore the influencing factors
Detailed Description:
With the gradual aging of Chinese population and continuous development of economy and society the incidence of cardiovascular disease and the number of patients have increased rapidly The National Heart Center has reported that the number of patients with clinically diagnosed cardiovascular disease in China has reached 290 million in 2016 240 million in 2014 Cardiovascular disease is the most common cause of death in humans Left ventricular systolic function plays an important role in the treatment and prognosis of patients with myocardial diseases Early sensitive detection of left ventricular systolic function timely treatment and early evaluation of the therapeutic effect can greatly reduce the death of patients with myocardial diseases rate
At present the left ventricular ejection fraction LVEF measured by the two-plane Simpson method in clinical is one of the methods to evaluating left ventricular systolic function It is especially suitable for patients with geometric deformation of the left ventricle but some early heart failure patients LVEF is still in the normal range whose systolic function has been reduced but In recent years 2D longitudinal strain is one of the indicators for evaluating left ventricular systolic function The researchers believe that 70 of cardiac function is obtained by longitudinal movement of myocardium which can be used as a good indicator for identifying myocardial diseases However both the two-plane Simpson method and the 2D longitudinal strain require good sound transmission conditions and good image quality You can clearly see the endocardium and epicardium Not all of patients in the clinic can get better image
Basic and clinical studies and clinical statistics show that tissue motion tracking of mitral annular displacement TMAD is not affected by image quality and can effectively evaluate left ventricular systolic function It can measure the mitral valve annulus displacement by marking the mitral valve annulus point and the reference point which can quickly and accurately evaluate the left ventricular longitudinal contraction function
At present the left ventricular ejection fraction LVEF measured by the two-plane Simpson method in clinical is one of the methods to evaluating left ventricular systolic function It is especially suitable for patients with geometric deformation of the left ventricle but some early heart failure patients LVEF is still in the normal range whose systolic function has been reduced but In recent years 2D longitudinal strain is one of the indicators for evaluating left ventricular systolic function The researchers believe that 70 of cardiac function is obtained by longitudinal movement of myocardium which can be used as a good indicator for identifying myocardial diseases However both the two-plane Simpson method and the 2D longitudinal strain require good sound transmission conditions and good image quality You can clearly see the endocardium and epicardium Not all of patients in the clinic can get better image
Basic and clinical studies and clinical statistics show that tissue motion tracking of mitral annular displacement TMAD is not affected by image quality and can effectively evaluate left ventricular systolic function It can measure the mitral valve annulus displacement by marking the mitral valve annulus point and the reference point which can quickly and accurately evaluate the left ventricular longitudinal contraction function
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None