Ignite Creation Date:
2024-05-05 @ 5:08 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00394940
Status:
COMPLETED
Last Update Posted:
2017-12-06
First Post:
2006-10-31
Brief Title:
Identifying Inflammatory Biomarkers of Chronic Obstructive Pulmonary Disease
Sponsor:
University of Arizona
Organization:
University of Arizona
Study Overview
Official Title:
Serum Inflammatory Biomarkers as Predictors of COPD Morbidity and Mortality
Status:
COMPLETED
Status Verified Date:
2017-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Chronic obstructive pulmonary disease COPD is a condition that is characterized by airway obstruction due to inflammation Levels of inflammatory proteins may be linked to when and to what extent COPD develops This study will use data collected during the Tucson Epidemiological Study of Airway Obstructive Disease TESAOD and its 33-year follow-up to determine the relationship between inflammatory protein expression and COPD
Detailed Description:
COPD is a term that encompasses both chronic bronchitis and emphysema two diseases that are characterized by airway obstruction that interferes with normal breathing Airway inflammation can stem from exposure to harmful fumes in the air chronic bacterial infections in the airways and a genetic predisposition to an inflammatory response to these agents In people with COPD the airway inflammation may extend beyond the lungs and contribute to systemic symptoms and ultimately to an increased mortality risk Markers of systemic inflammation have been identified but the relationship between these markers and when and to what extent COPD develops has not been determined This study will use data collected during the TESAOD and its 33-year follow-up to determine the relationship between COPD and the expression of various inflammatory proteins including pro-inflammatory cytokines eg IL-6 IL-8 TNF-alpha and acute phase proteins eg C-reactive protein soluble CD14
This study will not recruit any new participants Detailed respiratory phenotypic information and serum samples that were collected during the TESAOD study will be evaluated in conjunction with newly generated biomarker and protein information No new phenotypic data or biological specimens will be collected in this study
This study will not recruit any new participants Detailed respiratory phenotypic information and serum samples that were collected during the TESAOD study will be evaluated in conjunction with newly generated biomarker and protein information No new phenotypic data or biological specimens will be collected in this study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R21HL085195-01 | NIH | None | httpsreporternihgovquickSearchR21HL085195-01 |