Ignite Creation Date:
2024-05-05 @ 5:07 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00399620
Status:
UNKNOWN
Last Update Posted:
2009-01-12
First Post:
2006-11-14
Brief Title:
Chromogranin-A-Derived Peptides and Periodontitis in Diabetic Patients
Sponsor:
University Hospital Strasbourg France
Organization:
University Hospital Strasbourg France
Study Overview
Official Title:
Chromogranin-A-Derived Peptides in the Gingival Crevicular Fluid and the Saliva of Diabetic Patients With or Without Periodontitis
Status:
UNKNOWN
Status Verified Date:
2009-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Periodontitis is a chronic disease of the supporting tissue of the teeth characterized by bleeding and inflamed gingival resorption of alveolar bone This disease has a significant impact of the quality of life as the teeth become progressively mobile and may fall out spontaneously if no treatment is provided Periodontal disease has been cited as the sixth complication of diabetes mellitusChromogranins secretogranins are a family of proteins present in nervous endocrine and immune cells released with catecholamines during stress situations Chromogranin A CGA is the major member of this familyThe aim of this study is to determine the level of CGA and its derived peptides in the gingival crevicular fluid GCF of health or diabetic patients with and without periodontitisThen we want to determine the antimicrobial activity of these peptides
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None