Ignite Creation Date:
2024-05-05 @ 5:07 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00394784
Status:
WITHDRAWN
Last Update Posted:
2023-12-11
First Post:
2006-10-30
Brief Title:
Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream Isolates
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream Isolates
Status:
WITHDRAWN
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Study terminated due to no enrollment
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This research is important because it allows for the determination of resistance rates to antibiotics that may not be frequently tested by the clinical microbiology laboratory at University of Pittsburgh Medical Center UPMC-Presbyterian It also will provide antibiotic minimum inhibitory concentrations MICs for these pathogens which may help in identifying the best empiric antibiotic option for gram-negative blood stream infections based on known pharmacodynamic parameters
Detailed Description:
Bacterial cultures will be ordered in the normal clinical course of the management of patients in the liver transplant ICU by the medical team These cultures are then processed by the clinical Microbiology laboratory in the normal manner If these cultures grow a Gram-negative bacteria they are eligible for this study Typically the clinical Microbiology laboratory saves these bacteria for a period of time after the final microbiology report At this time unless asked otherwise the bacteria will be placed in biohazardous waste containers for proper disposal If these cultures have grown a Gram-negative bacteria they are eligible for this study and will not be disposed of but will be given to the investigators without identifiers for this study The antibiotic susceptibility of these organisms will be tested by the investigators in a separate research laboratory Mechanisms of antibiotic resistance may also be assessed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None