Ignite Creation Date:
2024-05-05 @ 5:06 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00385216
Status:
COMPLETED
Last Update Posted:
2020-11-24
First Post:
2006-10-05
Brief Title:
Nicotine as an Adjuvant Analgesic for Third Molar Surgery
Sponsor:
Columbia University
Organization:
Columbia University
Study Overview
Official Title:
Effect of Nicotine on Pain After Third Molar Extraction
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Third molar surgery is complicated by pain and swelling for several days after surgery Non-steroidal antiinflammatory drugs have been useful in combination with opioids for treatment Nicotine has antiinflammatory and pain relieving properties We will use nicotine or placebo as a nasal spray before surgery to determine whether nicotine affects pain or inflammation
Detailed Description:
This is a randomized double blind cross-over study In each of two sittings the third molars on one side of the mouth are removed In one sitting the subject will receive a nicotine nasal spray 3mg and in the other placebo VAS and narcotic utilization will be compared within patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None