Ignite Creation Date:
2024-05-06 @ 2:18 PM
Last Modification Date:
2024-10-26 @ 1:28 PM
Study NCT ID:
NCT04276974
Status:
COMPLETED
Last Update Posted:
2022-03-03
First Post:
2020-02-17
Brief Title:
Effects of an Organic Plant-rich Diet on Gut Microbiome and Vascular Function ORGAMIC Pilot Study
Sponsor:
Kings College London
Organization:
Kings College London
Study Overview
Official Title:
Effects of an Organic Plant-rich Diet on Gut Microbiome and Vascular Function the ORGAMIC Pilot Study
Status:
COMPLETED
Status Verified Date:
2022-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Previous work have shown that consumption of foods rich in polyphenols such as berries and cocoa led to beneficial changes in the gut microbiota composition as well as improvements in biomarkers of cardiovascular disease risk in healthy volunteers In addition recent studies suggest that pesticide exposure has a detrimental effect on the gut microbiome in human populations and laboratory animalsThe aim of this pilot study is to investigate the effects of short-term consumption of an organic and a non-organic plant rich diet on urinary polyphenol and pesticide levels gut microbiome and selected biomarkers of cardiovascular health in a group of young healthy individuals
Healthy men and women participants 10 will be recruited for a 2-arm randomised crossover controlled trial Urinary polyphenol and pesticide levels after consumption of an organic and non-organic plant rich diet for 4 days will be analysed Changes in gut microbiome composition and biomarkers of cardiovascular disease risk flow-mediated dilation blood pressure and arterial stiffness will also be investigated
Healthy men and women participants 10 will be recruited for a 2-arm randomised crossover controlled trial Urinary polyphenol and pesticide levels after consumption of an organic and non-organic plant rich diet for 4 days will be analysed Changes in gut microbiome composition and biomarkers of cardiovascular disease risk flow-mediated dilation blood pressure and arterial stiffness will also be investigated
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None